Research
Mixed
Epigenetic clocks, such as the DNAm PhenoAge and DunedinPoAm, can predict biological age, lifespan, and risk of chronic disease.
Epigenetic clocks are emerging tools to measure biological aging. While not yet standard clinical practice, they may eventually help individuals track the impact of lifestyle changes on their biological age.
GoodSupportsHIGH confidence
This clock measures our biological age and predicts our lifespan... DunedinPoAm... estimates the rate of aging in subjects... associated with an increased risk of chronic disease incidence and mortality in older men.
Why this rating
Multiple studies cited (Horvath, Levine, Belsky) support the validity of these clocks.
Source
Aging and aging-related diseases: from molecular mechanisms to interventions and treatments
Jun Guo et al. · Signal Transduction and Targeted Therapy · 2022
DOI 10.1038/s41392-022-01251-0
narrative_reviewCited 1,557×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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