Research
Cellular
Interventions aimed at increasing muscle protein synthesis are the most effective countermeasure for preventing, delaying, or reversing the loss of skeletal muscle mass experienced in various muscle wasting conditions.
Practitioners should focus on strategies that enhance muscle protein synthesis to combat muscle wasting.
StrongSupportsmedium confidence
we present evidence to suggest that interventions aimed at increasing muscle protein synthesis represent the most effective countermeasure for preventing, delaying, or reversing the loss of skeletal muscle mass experienced in various muscle wasting conditions.
Why this rating
Based on results from acute and chronic studies in humans.
Source
Resistance exercise and nutrition to counteract muscle wasting
Jonathan P. Little et al. · Applied Physiology Nutrition and Metabolism · 2009
DOI 10.1139/h09-093
reviewCited 100×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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