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Interventions aimed at increasing muscle protein synthesis are the most effective countermeasure for preventing, delaying, or reversing the loss of skeletal muscle mass experienced in various muscle wasting conditions.

Practitioners should focus on strategies that enhance muscle protein synthesis to combat muscle wasting.

StrongSupportsmedium confidence
we present evidence to suggest that interventions aimed at increasing muscle protein synthesis represent the most effective countermeasure for preventing, delaying, or reversing the loss of skeletal muscle mass experienced in various muscle wasting conditions.
Jonathan P. Little et al. · Applied Physiology Nutrition and Metabolism · 2009

Why this rating

Based on results from acute and chronic studies in humans.

Source

Resistance exercise and nutrition to counteract muscle wasting

Jonathan P. Little et al. · Applied Physiology Nutrition and Metabolism · 2009

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