Research
Cellular
Loss of muscle mass results from a decrease in muscle protein synthesis and/or an increase in muscle protein degradation.
Understanding these mechanisms can help in developing targeted interventions for muscle preservation.
StrongSupportsmedium confidence
Loss of muscle mass is the result of a decrease in muscle protein synthesis, an increase in muscle protein degradation, or a combination of both.
Why this rating
Based on established knowledge in the field.
Source
Resistance exercise and nutrition to counteract muscle wasting
Jonathan P. Little et al. · Applied Physiology Nutrition and Metabolism · 2009
DOI 10.1139/h09-093
reviewCited 100×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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