Research
Cellular
Individuals with type 2 diabetes mellitus (T2DM) exhibit more severe insulin resistance (IR) compared to similarly obese non-diabetic individuals, with IR measured at 6.1 +/- 2.3 mg x min(-1) x kg FFM(-1) for T2DM and 9.9 +/- 3.3 mg x min(-1) x kg FFM(-1) for non-DM (P < 0.01).
Practitioners should be aware that T2DM patients may require more intensive management of insulin resistance compared to non-diabetic obese individuals.
StrongSupportsmedium confidence
There was more severe IR in T2DM (6.1 +/- 2.3 vs. 9.9 +/- 3.3 mg x min(-1) x kg FFM(-1); P < 0.01).
Why this rating
Based on the comparison of insulin resistance between groups in a controlled study.
Source
Adipose tissue distribution in relation to insulin resistance in type 2 diabetes mellitus
Koichiro Azuma et al. · American Journal of Physiology-Endocrinology and Metabolism · 2007
DOI 10.1152/ajpendo.00394.2006
cross-sectional · n=102Cited 78×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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