Research
Cellular
Commencing endurance-based exercise with low muscle glycogen availability results in greater activation of signalling proteins compared to normal glycogen concentration.
Practitioners should consider the impact of glycogen levels on training adaptations.
StrongSupportsmedium confidence
Commencing endurance-based exercise with low muscle glycogen availability results in greater activation of many of these signalling proteins compared with when the same exercise is undertaken with normal glycogen concentration.
Why this rating
The abstract discusses established physiological responses to exercise.
Source
Ramping up the signal: promoting endurance training adaptation in skeletal muscle by nutritional manipulation
John A. Hawley et al. · Clinical and Experimental Pharmacology and Physiology · 2014
DOI 10.1111/1440-1681.12246
otherCited 73×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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