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Commencing high-intensity resistance exercise with low muscle glycogen availability does not compromise the anabolic signal and subsequent rates of MPS.
Practitioners can advise that low glycogen levels do not hinder the anabolic response to resistance training.
StrongSupportsmedium confidence
We conclude that commencing high-intensity REX with low muscle glycogen availability does not compromise the anabolic signal and subsequent rates of MPS.
Why this rating
Based on study design from abstract.
Source
Low muscle glycogen concentration does not suppress the anabolic response to resistance exercise
Donny M. Camera et al. · Journal of Applied Physiology · 2012
DOI 10.1152/japplphysiol.00395.2012
rct · n=16Cited 74×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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