Research
Cellular
A greater improvement in insulin sensitivity with weight loss during caloric restriction plus exercise may be related to improved coupling of β-oxidation and tricarboxylic acid cycle flux induced by exercise.
Practitioners should consider the role of exercise in enhancing insulin sensitivity during weight loss interventions.
StrongSupportsmedium confidence
A greater improvement in Si with weight loss during CR+EX interventions may be related to improved coupling of β-oxidation and tricarboxylic acid cycle flux induced by exercise.
Why this rating
Based on the randomized controlled trial design.
Source
Effect of Caloric Restriction with and without Exercise on Metabolic Intermediates in Nonobese Men and Women
Leanne M. Redman et al. · The Journal of Clinical Endocrinology & Metabolism · 2010
DOI 10.1210/jc.2010-1971
cross-sectional · n=46Cited 53×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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