Research
Cellular
Prolonged, intense weight-bearing exercise can increase intestinal permeability but effects are transient.
While intense exercise can temporarily affect gut health, these effects are not long-lasting.
StrongQualifiesmedium confidence
Prolonged, intense, weight-bearing exercise conducted in extreme conditions can increase intestinal permeability, compromising gut-barrier function and resulting in both upper and lower GI symptoms, these are transient and benign.
Why this rating
The abstract discusses established physiological responses to intense exercise.
Source
Exercise, the Gut Microbiome and Gastrointestinal Diseases: Therapeutic Impact and Molecular Mechanisms
John A. Hawley et al. · Gastroenterology · 2025
DOI 10.1053/j.gastro.2025.01.224
reviewCited 42×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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