Research
Cellular
PLIN3 knockdown results in drastic reductions in lipid oxidation in myotubes from lean individuals.
Reducing PLIN3 may significantly impair lipid oxidation in lean muscle cells, which could impact metabolic health.
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PLIN3 knockdown showed drastic reductions in lipid oxidation in myotubes from leans.
Why this rating
Based on experimental results from human myotubes.
Source
Perilipin 3 Differentially Regulates Skeletal Muscle Lipid Oxidation in Active, Sedentary, and Type 2 Diabetic Males
Jeffrey D. Covington et al. · The Journal of Clinical Endocrinology & Metabolism · 2015
DOI 10.1210/jc.2014-4125
cross-sectional · n=29Cited 40×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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