Research

Cellular

Treatment with brefeldin A (BFA) reduces lipid oxidation in cells from lean and T2D individuals, but not in active participants.

BFA may be a useful tool for studying lipid metabolism, but its effects vary significantly among different metabolic states.

StrongSupportsmedium confidence
Furthermore, treatment with BFA...reduced lipid oxidation in cells from lean and T2D, but not in active participants.
Jeffrey D. Covington et al. · The Journal of Clinical Endocrinology & Metabolism · 2015

Why this rating

Based on experimental results with clear outcomes reported.

Source

Perilipin 3 Differentially Regulates Skeletal Muscle Lipid Oxidation in Active, Sedentary, and Type 2 Diabetic Males

Jeffrey D. Covington et al. · The Journal of Clinical Endocrinology & Metabolism · 2015

DOI 10.1210/jc.2014-4125

cross-sectional · n=29Cited 40×
Read the paper
DOI resolved against Crossref · corpus check 2026-06-10

This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →