Research
Cellular
Creatine supplementation leads to greater muscle hypertrophy in the upper limbs (7.1 ± 2.9%) compared to lower limbs (3.2 ± 2.1%) and trunk (2.1 ± 2.2%) in resistance-trained young adult men.
Practitioners should consider creatine supplementation to enhance muscle growth, particularly in the upper body.
StrongSupportsmedium confidence
For the Cr group, improvements in ULLST (7.1 ± 2.9%) were higher than those observed in LLLST (3.2 ± 2.1%) and TLST (2.1 ± 2.2%).
Why this rating
Based on the randomized controlled trial design indicated in the abstract.
Source
Creatine supplementation elicits greater muscle hypertrophy in upper than lower limbs and trunk in resistance-trained men
João Pedro Nunes et al. · Nutrition and Health · 2017
DOI 10.1177/0260106017737013
rct · n=43Cited 28×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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