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Cellular
Calorie restriction was associated with a small but significantly lower number of WBC, lymphocytes, and monocytes.
Practitioners may observe changes in immune cell counts with calorie restriction in healthy adults.
StrongSupportsmedium confidence
In addition, CR was associated with a small, but significantly lower number of WBC, lymphocytes, and monocytes.
Why this rating
Based on a randomized controlled trial design.
Source
Effects of prolonged calorie restriction on inflammation and immune function: a randomized controlled trial in non‐obese humans (40.4)
Simin Nikbin Meydani et al. · The FASEB Journal · 2014
DOI 10.1096/fasebj.28.1_supplement.40.4
rct · n=218Cited 7×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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