Browse the evidence

Recent guidelines emphasize the importance of diagnosing and treating obesity to prevent CVD.

Clinicians should follow guidelines to effectively manage obesity in patients to reduce CVD risk.

Factors that mediate the long-term effectiveness of resistance exercise stimuli include optimizing dose and recovery.

Focus on optimizing training dose and recovery to enhance long-term strength outcomes.

Weight loss reduced CRP levels by 33.5% and IL-6 levels by 41.9%.

Weight loss can significantly lower inflammation markers associated with obesity.

Regular exercise promotes, maintains, and restores healthy functioning of nearly every physiological system of the human body.

Practitioners should encourage regular exercise as a key component of health maintenance.

Protein supplementation after exercise improves fat-free mass by 0.54 kg and skeletal muscle mass by 0.34 kg compared to placebo.

Practitioners should recommend protein supplementation after exercise to enhance muscle mass.

Protein supplementation at night improves handgrip strength by 2.85 kg and leg press strength by 12.12 kg compared to placebo.

Practitioners should consider recommending protein supplementation at night to improve strength.

Milk proteins, red meat, and mixed protein are effective for gains in both muscle mass and strength.

Practitioners should prioritize milk proteins and red meat in dietary recommendations for muscle gain.

Whey protein supplementation resulted in a greater increase in vastus lateralis muscle thickness (8.4 ± 2.5%) compared to leucine-matched collagen peptides (5.6 ± 2.6%) after a 10-week resistance training program.

Practitioners should consider whey protein as a more effective supplement for increasing muscle thickness in untrained individuals.

Whey protein supplementation led to a greater increase in biceps brachii muscle thickness (10.1 ± 3.8%) compared to leucine-matched collagen peptides (6.0 ± 3.2%) after a 10-week resistance training program.

Whey protein may be more effective than collagen peptides for increasing biceps muscle size in untrained individuals.

Exercise is a first-line prevention and intervention strategy for type 2 diabetes.

Practitioners should prioritize exercise as a key component in diabetes prevention and treatment.

Excess accumulation of visceral adipose tissue (VAT) leads to the clustering of cardiometabolic risk factors.

Reducing visceral fat may help mitigate cardiometabolic risks.

Exercise has emerged as a potent therapeutic in disease states characterized by the accelerated aging phenotype.

Implementing exercise programs can be crucial for managing diseases associated with aging.

Multimodal programs including performance, nutritional, and psychological interventions may improve postoperative outcomes for patients undergoing bariatric surgery.

Incorporating multimodal interventions may enhance the success of bariatric surgery for patients with dysglycemia.

Remote interventions are feasible for older adults and can support fidelity, adherence, engagement, and clinically significant weight loss.

Practitioners can confidently use remote interventions to promote healthy aging in older adults.

Higher protein intake (HP) and moderate protein intake (MP) groups showed greater increases in skeletal muscle mass (SMM) compared to the lower protein intake (LP) group, with increases of 5.1% and 5.4% respectively, versus 2.3% for LP (P < 0.05).

Practitioners should encourage higher protein intake in older women to enhance muscle gains during resistance training.

Protein intake is a moderating variable for body recomposition in older women undergoing resistance training, with low protein intake having a less favorable effect.

Emphasizing adequate protein intake is crucial for optimizing body recomposition in older women engaged in resistance training.

Exercise is a first-line prevention and intervention strategy for type 2 diabetes.

Practitioners should prioritize exercise as a key component in diabetes prevention and treatment.

Endurance exercise positively influences muscle protein turnover rates in people with obesity.

Incorporating HIIT may help improve muscle health in individuals with obesity.

Single-set resistance training performed to failure elicits greater hypertrophy gains compared to submaximal effort, although differences are modest.

Practitioners may consider incorporating training to failure for enhanced muscle growth.

Short-term resistance training combined with leucine-enriched protein supplementation increases integrated myofibrillar protein synthesis (MyoPS) rates in young adults.

Incorporating leucine-enriched protein bars may enhance muscle protein synthesis during resistance training.

Short-term resistance training increases integrated myofibrillar protein synthesis (MyoPS) compared to rest.

Resistance training is effective for increasing muscle protein synthesis.

Multi-ingredient supplementation (MIS) resulted in a greater increase in type II fiber cross-sectional area (fCSA) following 10 weeks of resistance exercise training (RET) compared to collagen supplementation (COL) (effect size = 0.89).

Practitioners may consider recommending multi-ingredient protein supplements to enhance muscle fiber growth during resistance training.

Sodium bicarbonate ingestion increased the number of repetitions performed in the third set of the bench press exercise (g: 0.30; p = 0.046).

Ingesting sodium bicarbonate may enhance performance in resistance training, particularly in later sets.

Sodium bicarbonate ingestion increased the total number of repetitions performed throughout all 3 sets in the bench press exercise (g: 0.23; p = 0.04).

Sodium bicarbonate may improve overall performance in resistance training sessions.