Browse the evidence

Refined carbohydrates contribute to the rising incidence of type 2 diabetes and cardiovascular disease in the Asian Indian population.

Highlight the risks of refined carbohydrates in dietary counseling for this population.

Whole grains such as amaranth, barley, brown rice, millet, and sorghum are nutritionally advantageous substitutes for refined carbohydrates.

Encourage the inclusion of whole grains in dietary recommendations for better health outcomes.

Metabolic surgery leads to a mean weight loss of 21.0% in mildly obese patients with T2DM over 5 years.

Practitioners can expect significant weight loss in patients undergoing metabolic surgery.

Intentional weight loss is associated with clinically relevant benefits for the majority of obesity-related comorbidities.

Practitioners should consider intentional weight loss strategies to improve obesity-related health outcomes.

Weight management strategies can lead to a reduction in obesity-related comorbidities and improvements in quality of life.

Implementing diverse weight management strategies can enhance health and quality of life for those with obesity.

Twins on the vegan diet experienced a significant mean decrease in body weight of -1.9 kg after 8 weeks.

Clinicians may recommend a vegan diet for weight loss in patients.

The high-fat diet prior to carbohydrate loading improved time trial performance.

Implementing a high-fat diet before carbohydrate loading may enhance cycling performance in trained athletes.

Healthy defaults reduced calories by 21.4%, fat by 43.9%, and sodium by 43.4% for kids' meal sides and beverages.

Adopting healthy defaults can lead to significant reductions in unhealthy nutrients in children's meals.

Obese individuals should not allow concerns about hazards of weight cycling to deter them from efforts to control their body weight.

Encourage obese clients to focus on weight management without fear of cycling.

Probiotics administration significantly reduced weight, BMI, waist circumference, waist to hip ratio, body fat percentage, and trunk fat percentage compared to the placebo group.

Incorporating probiotics may enhance weight loss and improve body composition in obese women with food addiction.

Once-weekly cagrilintide-semaglutide (at a dose of 2.4 mg each) resulted in a significantly lower body weight than placebo in adults with obesity and type 2 diabetes.

Practitioners can consider cagrilintide-semaglutide as an effective treatment for weight management in this population.

More patients in the cagrilintide-semaglutide group than in the placebo group had a weight reduction of 5% or more.

Cagrilintide-semaglutide may be particularly effective for achieving clinically significant weight loss.

In-clinic group visits resulted in a mean weight loss of -4.4 kg at 24 months.

In-clinic group visits may be an effective strategy for weight loss in rural settings.

Telephone group visits resulted in a mean weight loss of -3.9 kg at 24 months.

Telephone group visits can also support weight loss in rural populations.

In-clinic group visits resulted in statistically significantly greater weight loss compared to in-clinic individual visits.

Implementing group visits may enhance weight loss outcomes compared to individual visits.

Carbohydrate ingestion before exercise improves subsequent time trial performance compared with fat ingestion.

Endurance athletes should prioritize carbohydrate intake before performance to enhance time trial outcomes.

At 10-year follow-up, the mean total body weight loss was -42.4 ± 19.6 kg for gastric bypass and -27.4 ± 14.5 kg for gastric banding.

Gastric bypass may lead to greater long-term weight loss compared to gastric banding.

Non-exercise activity thermogenesis (NEAT) has a considerable potential impact on energy balance and weight gain.

Increasing NEAT could be a strategy for weight management.

Sustainable lifestyle modifications are critical for reducing morbidity and mortality from preventable conditions.

Emphasizing the need for sustainable lifestyle changes can guide health interventions.

Individuals with a low resting metabolic rate (RMR) for a given body size are at higher risk of significant weight gain, relative to those with a high RMR.

Practitioners should consider RMR when assessing weight gain risk in individuals.

For people with type 2 diabetes, an algorithm including lifestyle modification and anti-diabetic medications is suggested.

Health practitioners should implement lifestyle modifications and consider medication options for managing type 2 diabetes.

Smartphones provide a unique platform to aid in the delivery of behavioral weight loss programs.

Practitioners can consider integrating smartphone applications into weight loss programs.

Most weight loss apps lack evidence-based behavior change strategies.

Practitioners should critically evaluate the evidence base of weight loss apps before recommending them.

Semaglutide is associated with significant weight reductions primarily due to fat mass loss.

Practitioners can expect semaglutide to primarily aid in fat loss for overweight or obese patients.