Browse the evidence

Most ultraprocessed foods overlap with foods high in saturated fat, added sugars, and sodium.

Practitioners should consider the nutritional content of UPFs when advising clients.

Tirzepatide achieved similar 12-month TBWL% as R-ESG (13.2% vs. 13.4%, p = .9) and significantly more than semaglutide (13.2% vs. 8.1%, p = .04).

Tirzepatide may be a viable alternative for weight loss in patients post-sleeve gastrectomy, potentially outperforming semaglutide.

Discontinuation rates were strongly associated with copayment amount, increasing from 41% in the lowest quintile to 51% in the highest quintile.

Financial considerations significantly impact patient adherence to semaglutide treatment.

A significant global prevalence of inadequate omega-6 and seafood omega-3 fatty acid intakes exists, particularly in less-developed regions.

Efforts should be made to improve omega-6 and omega-3 intake in less-developed areas.

Management strategies for weight regain include lifestyle interventions, pharmacotherapy, and revisional surgery.

A multidisciplinary approach incorporating these strategies is essential for effective long-term weight management.

These therapies may reduce the risk for HF hospitalizations.

Incorporating these therapies may help reduce hospital admissions for heart failure in this patient population.

Finerenone has been associated with reduced cardiovascular mortality and total worsening HF events across all BMI levels, with greater benefits observed in patients with higher BMIs.

Finerenone may be a beneficial treatment option for reducing cardiovascular risks in patients with varying BMI levels.

Integrating shared decision-making (SDM) into obesity management enhances patient-centered care and has the potential to improve long-term outcomes.

Practitioners should consider incorporating SDM to enhance patient engagement and outcomes in obesity care.

Programs incorporating SDM reported improved patient engagement, satisfaction, and health outcomes across diverse demographic groups.

Incorporating SDM can lead to better patient experiences and outcomes in obesity management.

Common facilitators of SDM success include the use of decision aids, culturally tailored counseling, and multidisciplinary team involvement.

Healthcare providers should utilize decision aids and culturally tailored approaches to enhance SDM in obesity care.

Semaglutide is the most cost-effective treatment option in the severe obesity patient population and in first-tier cities in China.

In specific urban populations with severe obesity, semaglutide may be a preferred treatment option.

Lifestyle management was the most likely to be cost-effective under the willingness-to-pay threshold.

Lifestyle interventions should be prioritized for cost-effective obesity management.

Weight loss in the GLP-1 RA group was directly associated with bone loss at the total hip (TH) and femoral neck (FN).

Weight management strategies may need to consider potential impacts on bone health.

Roux-en-Y gastric bypass was associated with less gastroesophageal reflux disease (GERD)-related symptoms compared to sleeve gastrectomy.

Surgeons may prefer Roux-en-Y gastric bypass for patients concerned about GERD symptoms.

The study suggests that patient-delivered interventions may be effective in community and clinical settings for weight loss maintenance.

Consider exploring patient-delivered interventions in various settings for effective weight maintenance.

Male individuals lost a significantly larger proportion of weight as lean soft tissue (LST) compared to female individuals, with means of 0.33 kg and 0.25 kg respectively.

Practitioners should consider gender differences in body composition changes during weight loss interventions.

Quality of life outcomes generally showed improvements with incretin-based therapies (IBTs).

Clinicians can expect improvements in quality of life for patients using IBTs.

Fresh bread and rice consumption are associated with lower IBD risk.

Encouraging the consumption of fresh bread and rice may be beneficial for gut health.

Baseline body fat percentage was significantly associated with weight gains (r = 0.57) and fat mass gains (r = 0.59) during an 8-week high-fat overfeeding intervention.

Practitioners should consider baseline body fat percentage when assessing weight gain responses to overfeeding.

Body fat percentage was inversely associated with the energy cost of weight (r = -0.38) and fat mass (r = -0.40) gains.

Higher body fat percentage may indicate lower energy efficiency in gaining weight.

Innovative solutions are needed to implement sustainable lifestyle modification interventions for T2D.

Practitioners should advocate for and develop innovative strategies to enhance lifestyle intervention adherence.

Obesity increases the risk of postoperative complications following elective surgery.

Surgeons should consider obesity as a significant risk factor when planning surgeries.

An interdisciplinary approach is necessary for effective weight loss treatment in obese patients before joint replacement surgery.

Healthcare teams should collaborate across disciplines to optimize weight loss strategies for these patients.

People with physical disabilities (PWD) report more sedentary time compared to people without disabilities (PWoD) (β = 0.34; 95 % CI = 0.16-0.52, p < 0.001).

Practitioners should be aware that PWD may require tailored interventions to reduce sedentary behavior.