Browse the evidence

Both guidelines provide guidance for recommended physical activity levels but acknowledge any physical activity, even less than recommended, is better than inactivity.

Encourage patients to engage in any level of physical activity to reduce cardiovascular risk.

Aging and muscle disuse lead to the development of anabolic resistance and contribute to the loss of skeletal muscle mass.

Awareness of the effects of aging and disuse on muscle mass is crucial for intervention strategies.

Nitric oxide was significantly higher for high velocity resistance training (HVRT) compared to traditional resistance training (RT) after 30 minutes of exercise.

Practitioners may consider HVRT to enhance nitric oxide production in elderly hypertensive women.

GLP1-RA therapy appears safe and effective in patients with IBD.

GLP1-RA may be considered a treatment option for managing IBD.

Both the narrow pyramid (NPR) and wide pyramid (WPR) resistance training systems significantly improved bioimpedance vector analysis (BIVA) patterns compared to the control group (CON) after eight weeks.

Resistance training can effectively improve body composition metrics in older women.

The wide pyramid resistance training system (WPR) resulted in a greater increase in phase angle (PhA) compared to the narrow pyramid (NPR) and control (CON) groups.

Utilizing a wide pyramid training approach may enhance cellular health indicators in older women.

HMB may have a small, positive impact on fat-free mass (FFM) in athletes when protein intake is suboptimal (<1.6 g·kg-1·d-1).

Athletes with low protein intake may benefit from HMB supplementation for improving muscle mass.

GLP-1 receptor agonists have beneficial effects on atherosclerosis and cardiovascular disease.

Practitioners may consider GLP-1 receptor agonists as a treatment option for improving cardiovascular health in patients with obesity and type 2 diabetes.

MyoPS increased above REST in both untrained and trained states, with a greater increase in males.

Males may experience a greater increase in muscle protein synthesis following resistance training.

Environmental factors such as meal schedule, food contents, type of exercise, and sleep deprivation influence gut hormones and appetite.

Practitioners should consider these environmental factors when addressing appetite and weight management.

Both low velocity loss (LVL) and high velocity loss (HVL) resistance training programs resulted in similar increases in 1 repetition maximum (1 RM), maximal voluntary contraction (MVC), power output, and muscle thickness.

Practitioners can use either LVL or HVL resistance training to achieve similar strength and hypertrophy outcomes.

The study utilized a within person, between leg design to compare the effects of different velocity loss thresholds.

The study design enhances the reliability of the results.

Insulin dynamics, such as insulin sensitivity or insulin secretion status, may interact with diets that vary in macronutrient composition.

Understanding insulin dynamics can help in designing more effective dietary interventions.

Current dietary guidelines recommend a spectrum of dietary composition for the general population.

Dietary recommendations should consider individual metabolic differences.

Twenty-four-hour energy expenditure (EE) on the resistance exercise (REX) day was 2,328 +/- 327 kcal.d(-1), which is greater than the control day (CON) at 2,001 +/- 369 kcal.d(-1), p < 0.001.

Resistance exercise significantly increases total daily energy expenditure in women.

The net increase in energy expenditure during and immediately after exercise represented 76 +/- 12% of the total increase in 24-hour EE.

Most of the increase in energy expenditure from resistance exercise occurs during and shortly after the workout.

Insulin dynamics, such as insulin sensitivity or insulin secretion status, may interact with diets that vary in macronutrient composition.

Dietary recommendations may need to consider an individual's insulin dynamics.

Current dietary guidelines recommend a spectrum of dietary composition for the general population.

Practitioners should be aware of the broad dietary guidelines applicable to the general population.

Obesity is associated with and likely has a direct causal role in the onset, progression and severity of chronic kidney disease.

Practitioners should consider the impact of obesity on chronic kidney disease management.

Obesity and chronic kidney disease place a significant burden on the health care delivery system.

Healthcare providers should be aware of the systemic impacts of obesity and CKD.

Calorie restriction and CREX elicited similar overall clinical responses to energy deficit.

Both calorie restriction and exercise combined with calorie restriction can lead to similar health outcomes, which may inform dietary and exercise recommendations.

Metabolic adaptation plays a relevant role in the management of obesity and human weight loss.

Practitioners should consider metabolic adaptation when designing weight loss interventions.

Drop set training may be an effective strategy to enhance muscular adaptations.

Practitioners may consider incorporating drop set training to potentially enhance muscle growth.

N-3 PUFA had no added benefit on muscle protein synthesis (MPS) but showed a trend towards increased absolute synthesis rates (ASR) during weeks 4–6 of resistance exercise training.

While n-3 PUFA may not significantly enhance MPS, it could still support muscle adaptation during resistance training.