Browse the evidence

Total repetitions to volitional fatigue was higher in females compared to males for both lifts.

Female beginners may have better endurance in deadlifting.

Suboptimal diet contributes to an estimated 3.04 million new cancer cases among US adults aged 20 years or older over a lifetime.

Healthcare practitioners should be aware of the significant impact of diet on cancer incidence.

Suboptimal diet is associated with an estimated 1.74 million cancer deaths among US adults aged 20 years or older over a lifetime.

Dietary interventions may significantly reduce cancer mortality rates.

Diet-attributable cancer burdens are higher among younger adults, men, non-Hispanic Blacks, and individuals with lower education and income attainments.

Targeted dietary interventions may be necessary for at-risk populations to reduce cancer burdens.

Medication intake was significantly reduced among participants in the DSMES program.

Reducing medication intake can be a positive outcome of effective diabetes management programs.

Diabetes-related emergency department visits among participants were below national averages.

Effective diabetes management can lead to fewer emergency health interventions.

Gynecologists play a pivotal role in the multidisciplinary approach to obesity management during menopause.

Gynecologists should integrate obesity management into routine care for menopausal women.

GLP-1 receptor agonists (GLP-1RAs) and combination therapy led to a significant decrease in mean glycated hemoglobin (HbA1c) levels by −3.5% at 12 months compared to DPP-4 inhibitors.

Practitioners can consider GLP-1RAs and combination therapy as effective options for managing HbA1c in liver transplant recipients with diabetes.

Alanine aminotransferase levels decreased with GLP-1RA and combination therapy.

Practitioners may consider monitoring liver enzyme levels when prescribing GLP-1RAs and combination therapy.

Adherence to VLCHF diets is likely poor without intensive support from health professionals.

Health professionals should provide ongoing support for individuals on VLCHF diets.

Dual-agonist and tri-agonist administration generally result in greater weight loss compared to GLP-1R agonists used alone.

Practitioners may consider dual- and tri-agonist therapies for enhanced weight loss in patients.

Combination therapies improve blood sugar and lipid levels compared to GLP-1R agonists alone.

Combination therapies may be beneficial for managing blood sugar and lipid levels in patients.

Emerging gut-peptide therapies further improve metabolic health outcomes for various metabolic diseases.

Practitioners should consider gut-peptide therapies for improving metabolic health in patients with metabolic diseases.

Blood pressure decreased by approximately 5 mm Hg after the carbohydrate-restricted diet.

A carbohydrate-restricted diet may help lower blood pressure in firefighters.

In males with type 2 diabetes, an intensive lifestyle intervention increased testosterone levels by 14% at year 1.

Practitioners should be aware of the increase in testosterone levels in males following weight loss interventions.

Changes in waist circumference due to the intensive lifestyle intervention were a significant mediator of sex hormone changes.

Practitioners should consider waist circumference changes when evaluating hormone level changes in patients.

New medications for patients with type 2 diabetes generally do not need adjustment with exercise.

Clinicians can reassure patients that new diabetes medications typically do not require exercise-related adjustments.

Four nights of sleep restriction reduced low-dose insulin glucose infusion rate (GIR) by 20% and high-dose insulin GIR by 12% in postmenopausal women.

Practitioners should consider the impact of sleep restriction on insulin sensitivity in postmenopausal women.

Youth with type 1 diabetes who achieved 4 goals had a higher insulin sensitivity (7.4 ± 4.1 mg/kg/min) compared to those who met 0-3 goals (5.2 ± 3.4 mg/kg/min, P = .04).

Practitioners should encourage adolescents with type 1 diabetes to meet ADA/ISPAD goals to improve insulin sensitivity.

Youth who achieved 5-6 goals had a higher insulin sensitivity (8.5 ± 4.3 mg/kg/min) compared to those who met 0-3 goals (5.2 ± 3.4 mg/kg/min, P = .003).

Practitioners should encourage adolescents with type 1 diabetes to meet ADA/ISPAD goals to improve insulin sensitivity.

15 dietary risk factors have probable or convincing evidence of causal effects on CVD or diabetes.

Practitioners should consider these dietary risk factors when addressing CVD and diabetes.

Two days of recovery with optimal energy availability (OEA) partially restored performance but did not fully recover it to the level of the OEA group.

Recovery strategies should include optimal energy availability to aid performance recovery after low energy phases.

The intensive lifestyle intervention may need to be sustained to reduce long-term health care spending.

Practitioners should consider the importance of ongoing support for lifestyle interventions to maintain benefits.

Resistance-trained individuals are capable of high absolute RIR accuracy when predicting 1 and 3 RIR on the barbell bench press exercise.

Practitioners can use RIR prescriptions to effectively gauge proximity to failure during resistance training.