Browse the evidence

The food industry influences government nutrition policies and marketing practices.

Awareness of industry influence can guide healthier food choices.

The food industry prioritizes economic interests over health in its marketing strategies.

Recognizing the economic motivations can help consumers make informed choices.

In general populations, fish consumption of 350 g/week or more is not associated with risk of major CVD or total mortality.

For the general population, increasing fish intake beyond 350 g/week may not provide additional cardiovascular benefits.

Neither glycogen depletion nor phosphorylation of relevant signalling proteins showed any difference between conditions of load and repetition duration.

Resistance training outcomes are not influenced by glycogen depletion or signalling protein changes based on load or repetition duration.

Significant gaps remain for achieving equity in nutrition security across the life span.

Efforts must be made to address gaps in nutrition security for all age groups.

The prevalences of type 2 diabetes and stroke mortality are higher in all Asian American subgroups compared with non-Hispanic White adults.

Health care professionals should prioritize screening for type 2 diabetes and stroke in Asian American populations.

Atherosclerotic cardiovascular disease risk is highest among South Asian and Filipino adults but lowest among Chinese, Japanese, and Korean adults.

Targeted interventions may be necessary for South Asian and Filipino populations to address higher cardiovascular risks.

Current pharmacologic options for obesity management are largely limited in number and of modest efficacy/safety profile.

Practitioners should be aware of the limitations of existing obesity medications.

There is an urgent need for safe and more efficacious new agents for obesity treatment.

There is a pressing need for practitioners to seek out and consider new treatment options.

Emerging pharmacologic agents and alternative approaches targeting obesity pathways are being explored.

Practitioners should stay informed about new pharmacologic agents and alternative approaches in obesity treatment.

Acute RT-induced hormonal elevations seem not to be directly correlated with muscle growth.

Practitioners should be cautious in assuming that increased hormonal levels from acute training will directly lead to muscle growth.

Greater numbers of participants correlated with smaller differences in weight loss.

Larger studies may yield more conservative estimates of diet effectiveness.

The mean effect of individualized lifestyle interventions for weight reduction in people with SMI is statistically significant but clinically insignificant.

Practitioners should be aware that while interventions may show statistical benefits, the practical impact on weight may be limited.

Pioglitazone and GLP-1 receptor agonists are promising treatments for NAFLD that also benefit the vasculature.

Clinicians may consider these medications for managing NAFLD and associated cardiovascular risks.

There was no significant effect of whey or soy alone on LBM change.

Neither whey nor soy protein alone is effective for increasing LBM.

SCD1 is a key enzyme that regulates energy homeostasis and various physiological processes.

Understanding SCD1's role can help in targeting metabolic diseases.

Aberrant activation of SCD1 contributes to obesity, non-alcoholic fatty liver, diabetes, and cancer.

Targeting SCD1 may help in managing these metabolic diseases.

Psychotropic drug-related weight gain (PDWG) is highly associated with non-initiation, discontinuation, and dissatisfaction with psychiatric drugs.

Practitioners should be aware of the impact of PDWG on patient adherence to psychiatric medications.

No difference was found between RTF and RTNF on maximal strength in overall analysis (SMD: -0.08; p = 0.642).

Both training methods may be equally effective for improving maximal strength.

No significant changes in quadriceps cross-sectional area were observed in the low-load not to failure group.

Avoid low-load training without reaching muscle failure if hypertrophy is the goal.

Higher genetically determined BMI is not associated with insulin secretion.

This suggests that BMI may not directly influence insulin secretion, which could inform treatment approaches.

Significant disproportionality for semaglutide remained in patients with coreported use of antidepressants and benzodiazepines.

Clinicians should consider the interaction of semaglutide with antidepressants and benzodiazepines when assessing risk.

Randomised controlled trials have not provided conclusive evidence that physical activity started during adulthood extends lifespan.

Caution should be exercised in claiming lifespan benefits from adult physical activity alone.

The health-related benefits of exercise have not yet translated into a proven causal relationship with longevity.

While exercise is beneficial, its direct impact on longevity remains unproven.