Browse the evidence

Adequate nutritional support is a secondary countermeasure to mitigate muscle loss.

Nutritional support should be integrated alongside resistance training to enhance muscle retention.

Countermeasures for muscle wasting should focus on stimulating anabolism rather than alleviating catabolism.

Focus on strategies that enhance muscle growth rather than just preventing muscle breakdown.

Muscle activity was highest during the partial back squat for gluteus maximus, biceps femoris, and soleus compared to the full back squat.

Practitioners may consider incorporating partial back squats to enhance activation of key muscle groups.

Practical interventions focused on dietary protein manipulation are proposed to prevent the onset of anabolic resistance.

Implementing dietary changes can be a proactive approach to combat age-related muscle loss.

Probiotics administration significantly reduced weight, BMI, waist circumference, waist to hip ratio, body fat percentage, and trunk fat percentage compared to the placebo group.

Incorporating probiotics may enhance weight loss and improve body composition in obese women with food addiction.

Once-weekly cagrilintide-semaglutide (at a dose of 2.4 mg each) resulted in a significantly lower body weight than placebo in adults with obesity and type 2 diabetes.

Practitioners can consider cagrilintide-semaglutide as an effective treatment for weight management in this population.

More patients in the cagrilintide-semaglutide group than in the placebo group had a weight reduction of 5% or more.

Cagrilintide-semaglutide may be particularly effective for achieving clinically significant weight loss.

The percentage of patients who had a glycated hemoglobin level of 6.5% or less was significantly higher in the cagrilintide-semaglutide group compared to the placebo group.

This treatment may significantly improve glycemic control in patients with type 2 diabetes.

In-clinic group visits resulted in a mean weight loss of -4.4 kg at 24 months.

In-clinic group visits may be an effective strategy for weight loss in rural settings.

Telephone group visits resulted in a mean weight loss of -3.9 kg at 24 months.

Telephone group visits can also support weight loss in rural populations.

In-clinic group visits resulted in statistically significantly greater weight loss compared to in-clinic individual visits.

Implementing group visits may enhance weight loss outcomes compared to individual visits.

Resistance training (RT) can elicit similar health benefits to aerobic training (AT).

Practitioners should consider incorporating RT alongside AT for optimal health benefits.

Engaging in resistance training can improve healthy aging, mobility, cognitive function, cancer survivorship, and metabolic health.

Incorporating RT can enhance various aspects of health, particularly in at-risk populations.

Regular resistance training is associated with a lower mortality risk.

Encouraging regular RT can be a strategy to reduce mortality risk.

Carbohydrate ingestion before exercise improves subsequent time trial performance compared with fat ingestion.

Endurance athletes should prioritize carbohydrate intake before performance to enhance time trial outcomes.

Poor nutrition is the leading cause of poor health, health care spending, and lost productivity in the United States and globally.

Practitioners should prioritize addressing nutrition to improve health outcomes.

Postexercise supplementation with protein-carbohydrate (PRO-CHO) resulted in similar increases in strength after a resistance exercise training program as compared with creatine-dextrose (CR-CHO).

Both protein-carbohydrate and creatine supplements can be effective for strength gains in untrained individuals.

Total body mass increased more for the creatine-dextrose group compared to the protein-dextrose group.

Creatine supplementation may lead to greater increases in total body mass compared to protein supplementation.

At 10-year follow-up, the mean total body weight loss was -42.4 ± 19.6 kg for gastric bypass and -27.4 ± 14.5 kg for gastric banding.

Gastric bypass may lead to greater long-term weight loss compared to gastric banding.

Protein supplementation, especially milk proteins, potentiate muscle protein synthesis, lean mass and exercise recovery.

Athletes should consider milk protein supplements to enhance muscle recovery and growth.

Non-exercise activity thermogenesis (NEAT) has a considerable potential impact on energy balance and weight gain.

Increasing NEAT could be a strategy for weight management.

The improvement in the 10-meter walking test (10-MWT) after an 8-week resistance training program is associated with increases in lower limb muscular strength (KE1RM) by 8.6% and muscle quality index (MQI) by 7.2%.

Resistance training can effectively improve walking speed in older women by enhancing muscular strength and quality.

Resistance training resulted in significant changes in body composition, including a decrease in fat mass by 1.4% and an increase in fat-free mass by 1.6%.

Resistance training can positively affect body composition in older women by reducing fat mass and increasing fat-free mass.

Sustainable lifestyle modifications are critical for reducing morbidity and mortality from preventable conditions.

Emphasizing the need for sustainable lifestyle changes can guide health interventions.