Browse the evidence

Lower dietary protein quality can potentially lead to inadequate utilizable protein intakes, especially for the elderly and some vegetarians and vegans.

Practitioners should consider dietary protein quality when advising elderly individuals and those following vegetarian or vegan diets.

A greater intake of plant fat is associated with a lower risk for overall mortality (HRs, 0.91) and cardiovascular disease (CVD) mortality (HRs, 0.86), particularly from grains and vegetable oils.

Encouraging higher plant fat intake, especially from grains and oils, may benefit longevity.

A higher intake of total animal fat is associated with an increased risk for overall mortality (HRs, 1.16) and CVD mortality (HRs, 1.14).

Reducing animal fat intake may lower mortality risk.

Retatrutide (LY3437943) is relatively safe and supports once-weekly dosing.

Practitioners can consider retatrutide as a potentially safe option for treatment with a convenient dosing schedule.

Retatrutide may be superior to dulaglutide in reducing plasma glucose and body weight.

Practitioners may consider retatrutide as a potentially more effective option than dulaglutide for managing diabetes.

Pharmacologic interventions targeting modifiable cardiometabolic risk factors are a reasonable strategy to prevent CVD development and progression of MASLD.

Practitioners should consider pharmacologic interventions for patients with MASLD to mitigate CVD risk.

Resmetirom has shown positive effects regarding CVD risk in the context of MASLD treatment.

Consider resmetirom as a potential treatment option for patients with MASLD at risk for CVD.

The degree of capillarization in muscle is associated with the change in type II fiber CSA following resistance training.

Improving muscle capillarization may enhance the effectiveness of resistance training.

Obesity is a significant predisposing factor for heart failure with preserved ejection fraction (HFpEF).

Practitioners should consider obesity as a critical factor in managing patients with HFpEF.

Semaglutide treatment resulted in a 17% reduction in new-onset atrial fibrillation (AF) incidence compared to controls.

Semaglutide may be an effective treatment option for reducing the risk of new-onset AF in patients.

In trials without SGLT2 inhibitors, there was a significant reduction of 21% in new-onset AF.

Semaglutide may be more effective in reducing AF risk when not used with SGLT2 inhibitors.

Muscle size increases vary across regions within and between muscles after resistance training programs.

Practitioners should consider regional differences in muscle hypertrophy when designing training programs.

Muscle architectural changes after resistance and stretch training programs are region-specific.

Training programs should account for region-specific changes in muscle architecture.

Fifteen states provide or propose to provide screening for food insecurity and referral to food security programs.

Practitioners can leverage state programs for food insecurity screening and referrals.

Thirteen states provide or propose to provide coverage of nutrition education services.

Practitioners should consider the availability of nutrition education services in their states.

Tai Chi exercise therapy significantly decreases triglyceride (TG) levels by an average of 0.23 mmol/L and increases high-density lipoprotein cholesterol (HDL-C) levels by an average of 0.15 mmol/L in patients with T2DM.

Tai Chi can be recommended to improve lipid profiles in T2DM patients.

Treatment with SAR425899 resulted in a smaller reduction in body composition-adjusted sleeping metabolic rate (SMR) compared to placebo (p = 0.002).

SAR425899 may help mitigate metabolic adaptation during weight loss.

Fat oxidation and ketogenesis increased in both groups, with significantly greater increases in the SAR425899 group (p < 0.05).

SAR425899 may enhance fat metabolism, which could support weight loss efforts.

There was no increased risk of IBD-specific adverse events associated with semaglutide use.

Semaglutide can be considered safe for use in IBD patients without increasing the risk of adverse events.

Probiotics and prebiotics support gut health and immune function, which are integral to effective recovery.

Including probiotics and prebiotics in recovery nutrition can enhance gut health and immune function.

Semaglutide is associated with cardiovascular risk reduction.

Practitioners can consider semaglutide as a potential option for reducing cardiovascular risk in adults.

Moderate coffee consumption is not associated with increased risk of CVD.

Health professionals can reassure patients that moderate coffee intake is safe regarding CVD risk.

Both groups experienced an improvement in cardiometabolic risk markers after 12 months.

Improvements in cardiometabolic health may accompany weight loss in postmenopausal women.

Mean total daily energy expenditure (TEE) for female soccer players was 2693 ± 432 kcal·d-1 over 12 days.

Practitioners should consider these energy expenditure values when planning nutrition for female soccer players.