Browse the evidence

The undulating-periodized resistance training program significantly reduced systolic and diastolic blood pressure by -4.5 mmHg and -4.0 mmHg, respectively.

The undulating-periodized training can be effective for lowering blood pressure in older adults.

Weight-loss medications approved for long-term use can help achieve medically significant weight loss when used as an adjunct to lifestyle changes.

Practitioners should consider weight-loss medications as a viable option for patients struggling to lose weight through lifestyle changes alone.

Substitution of LNCSBs for sugar-sweetened beverages (SSBs) was associated with lower incidence of obesity (RR, 0.88) and coronary heart disease (RR, 0.89).

Replacing SSBs with LNCSBs may reduce obesity and heart disease risk.

Substitution of water for SSBs showed lower weight (MD, -0.10 kg/y) and lower incidence of obesity (RR, 0.85).

Encouraging water over SSBs can aid in weight loss and reduce obesity risk.

Nutritional interventions can promote fatty acid oxidation and modify subsequent exercise capacity.

Implementing specific nutritional strategies may enhance fat utilization and improve performance in athletes.

Short-term and long-term adaptation to a high-fat diet affects metabolism, training capacity, and performance during endurance and ultra-endurance exercise.

Athletes may benefit from both short-term and long-term high-fat dietary strategies to enhance endurance performance.

Lifestyle intervention reduced visceral fat at L2-L3 by 24.3% in men and 18.2% in women.

Implementing lifestyle changes can significantly reduce visceral fat, which may lower diabetes risk.

Lifestyle intervention led to a reduction in body weight of 8.2% in men and 7.8% in women.

Encouraging lifestyle modifications can effectively reduce body weight in at-risk populations.

Decreased diabetes risk was associated with reductions in body weight, BMI, and central body fat distribution after lifestyle intervention.

Reducing body weight and central fat through lifestyle changes can significantly lower diabetes risk.

A Mediterranean-style diet reduced the need for glucose-lowering drugs more than a low-fat diet in patients with newly diagnosed type 2 diabetes.

Practitioners may consider recommending a Mediterranean-style diet to patients with newly diagnosed type 2 diabetes to potentially reduce the need for glucose-lowering medications.

Ingesting protein prior to resistance exercise enhances signaling and muscle protein synthesis (MPS) in skeletal muscle.

Practitioners should consider protein ingestion timing to enhance muscle synthesis post-exercise.

Time restricted eating (TRE) will not be inferior to current practice (CP) in improving glycaemic control in individuals at risk of type 2 diabetes.

TRE may be a viable alternative dietary strategy for improving glucose control in at-risk individuals.

The for-profit worksite had almost twice the weight loss of the non-profit worksite over 6 months (−11.2±7.7 kg vs. −6.2±5.4 kg; P=0.0002).

For-profit worksites may be more effective for weight loss interventions compared to non-profit worksites.

Weight change was predicted by initial BMI (p=0.009) and income (p=0.03).

Initial BMI and income should be considered when designing weight loss programs.

Both control sites gained weight on average while the intervention sites lost weight.

Weight loss interventions at worksites can be effective, contrasting with control conditions.

Encouraging frequent self-weighing can improve the efficacy of weight loss programs at a national level.

Practitioners should consider integrating self-weighing into weight loss programs to enhance effectiveness.

Each additional weigh-in led to an average increase in weight loss of 0.131 lbs.

Encouraging users to weigh themselves more frequently may lead to greater weight loss outcomes.

Mean self-weighing frequency was higher in the treatment group compared to the control group.

Increasing the frequency of self-weighing can be a simple intervention to enhance weight loss efforts.

The HLC diet was more effective for improving the triglyceride to HDL-cholesterol ratio (TG/HDL-C) compared to the HLF diet.

The HLC diet may be preferred for improving lipid profiles in overweight adults.

Participants collectively lost 6,559 lbs over 12 months with a retention rate of 79%.

Weight loss interventions can be effective in a diverse group of healthy adults.

Weight loss was similar for Healthy Low-Fat and Healthy Low-Carbohydrate diets: -12.1 ± 1.1 lbs vs. -13.8 ± 1.0 lbs.

Both diet types can lead to similar weight loss outcomes.

Semaglutide is endorsed for obesity treatment following its FDA approval for type 2 diabetes.

Health practitioners can consider semaglutide as a treatment option for obesity.

Within both the Healthy Low-Fat (HLF) and Healthy Low-Carbohydrate (HLC) diet arms, the 12-month decrease in BMI was significantly greater for those in the High Quality/High Adherence subgroups compared to the Low Quality/Low Adherence subgroups.

Practitioners should emphasize the importance of both dietary quality and adherence for effective weight loss.

Improvement in dietary quality and adherence may influence weight loss success among those following low-fat and low-carbohydrate diets.

Encourage clients to improve both the quality of their diet and their adherence to dietary plans for better weight loss outcomes.