Research
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High responders to hypertrophic strength training showed a decrease of -10.5% in vastus lateralis cross-sectional area (VLCSA) during detraining.
Practitioners should be aware that high responders may experience significant muscle loss during periods of detraining.
StrongSupportsmedium confidence
During detraining, HR showed a decrease of -10.5% in VLCSA.
Why this rating
Based on the study design involving resistance training and detraining with measurable outcomes.
Source
High Responders to Hypertrophic Strength Training Also Tend to Lose More Muscle Mass and Strength During Detraining Than Low Responders
Aapo Räntilä et al. · The Journal of Strength and Conditioning Research · 2021
DOI 10.1519/jsc.0000000000004044
cohort · n=24Cited 15×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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