Browse the evidence

In 2018, the mean global intake per person of unprocessed red meat was 51 g/day, with 17 countries having mean intakes of at least one serving (100 g) per day.

Practitioners should be aware of the significant global consumption of unprocessed red meat and target interventions accordingly.

Between 1990 and 2018, global intakes of unprocessed red meat, eggs, milk, processed meat, seafood, and cheese increased.

This trend indicates a growing consumption of certain animal-source foods, which may have implications for public health and nutrition policies.

There is a need for the development of highly efficacious and safe new agents for obesity treatment.

Healthcare providers should advocate for and support the development of new obesity treatments.

The food industry in the United States generated nearly $900 billion in sales in 2000.

Understanding the scale of the food industry can inform marketing strategies.

Substituting water for SSBs was not associated with any outcome.

Practitioners should note that water substitution does not yield measurable benefits in this context.

Guidelines scored poorly on AGREE II criteria, particularly in rigor of development, applicability, and editorial independence.

Health officials should critically evaluate the guidelines before dissemination.

Further research is needed to provide a clear differentiation between short and long inter-set rest intervals.

Researchers should conduct more studies to clarify the effects of different rest intervals.

There are significant research disparities in the data available on Asian American adults in risk prediction models, national surveillance surveys, and clinical trials.

More inclusive research efforts are needed to address health disparities in Asian American populations.

GI181771X did not reduce body weight in obese patients.

Practitioners should be aware that GI181771X is not effective for weight loss in the studied population.

There is ongoing research to discover orally active compounds that mimic the effects of exercise training, referred to as 'exercise pills'.

Research into exercise mimetics may provide alternatives to traditional exercise for health benefits.

There is no significant effect of exercise order on muscle hypertrophy (ES = 0.03; p = 0.862).

Exercise order may not need to be a primary concern for hypertrophy outcomes.

Daily energy deficit was not significantly associated with change in cognitive test performance.

Practitioners should note that energy deficits from dieting may not impact cognitive performance.

The U.S. Department of Agriculture's 1991 withdrawal of its Eating Right Pyramid food guide was influenced by pressure from meat and dairy producers.

Practitioners should be aware of the potential influence of food industry lobbying on dietary guidelines.

There is a conflict of interest in the Department of Agriculture's dual mandates to promote U.S. agricultural products and to advise the public about healthy food choices.

Practitioners should be aware of potential biases in dietary recommendations due to conflicting interests.

More randomized clinical trials are needed to examine the relative utility of different dietary factors in the treatment of obesity.

There is a need for more research to identify effective dietary strategies for obesity treatment.

Significant disproportionality was detected for semaglutide-associated suicidal ideation (ROR, 1.45; 95% CI, 1.18-1.77; IC, 0.53; 95% CI, 0.19-0.78).

Clinicians should be aware of the potential risk of suicidal ideation in patients treated with semaglutide.

A total of 107 cases of suicidal and/or self-injurious ADRs were reported with semaglutide.

Awareness of the number of reported cases can inform risk assessments for semaglutide use.

The pooled effect on adiponectin from fish feeding was not statistically significant (-0.01 μg/mL, 95% CI -0.65; 0.64, P = 0.99).

Fish feeding may not be an effective method for increasing adiponectin levels.

Modifications to a whole room indirect calorimeter allow accurate measurement of energy expenditure in 1-min intervals.

Practitioners can use this modified calorimeter to study acute effects of food, exercise, or drugs on energy expenditure.

Nutrition researchers and professional societies need to recognize the influence of food-industry sponsorship.

Practitioners should be aware of the potential biases introduced by food-industry funding.

Sponsored studies should promote public health.

Practitioners should ensure that research aligns with public health goals.

There was no difference in 24-h energy expenditure (EE) between Caucasian and Pima Indian men (2,422 vs. 2,523 kcal/24 h).

Practitioners should note that ethnic differences may not significantly affect energy expenditure in these populations.

The subsidy policy for fruits and vegetables would not significantly affect obesity and type 2 diabetes.

Subsidizing fruits and vegetables may not be an effective strategy for reducing obesity and diabetes.

The highest achieved tertiles of EPA and DHA were associated with neither benefit nor harm in patients at high cardiovascular risk.

Practitioners should note that increasing EPA and DHA levels may not provide cardiovascular benefits in high-risk patients.