Browse the evidence

SGLT2 inhibitors contribute to weight loss and fat reduction through glucosuria.

Incorporating SGLT2 inhibitors may aid in weight management for diabetic patients.

Obesity is linked to a significantly higher chance of early death from associated comorbidities.

Healthcare providers should monitor comorbidities in obese patients.

Nearly 62% of primary care patients are overweight or obese.

Healthcare providers should be aware of the high prevalence of obesity among their patients.

Patients prefer to receive weight management support from GPs rather than other health professionals.

GPs should recognize their important role in providing weight management support to patients.

Cereal fiber intake (about two whole-grain bread slices per day) was associated with a 14% lower risk of myocardial infarction or stroke.

Increasing cereal fiber intake may lower the risk of myocardial infarction or stroke in older adults.

Moderate and high leisure-time activity predicted 28% and 44% lower mortality, respectively, compared with little activity.

Encouraging moderate to high leisure-time activity can significantly reduce mortality risk in older adults.

The new U.S. dietary guidelines will affect Americans' diets through federal food policies and food-assistance programs.

Practitioners should consider how federal policies may influence dietary choices.

Energy intake during the ad libitum period increased to 4550 +/- 921 kcal/d, resulting in a spontaneous overeating by 54 +/- 32% above weight maintenance requirement.

Practitioners should be aware that ad libitum intake can significantly exceed maintenance needs, leading to weight gain.

Weight gain during the 6-week holiday season explained 51% of annual weight gain.

Practitioners should consider the significant role of holiday weight gain in annual weight management.

The mean total costs over 2 years were lower for MBS ($51,794) compared to GLP-1 receptor agonists ($63,483).

MBS may offer a more cost-effective long-term solution for obesity treatment.

Dilution of protein in the diet by readily digestible carbohydrates leads to excess calorie intake and obesity.

Encouraging higher protein intake relative to carbohydrates may help mitigate obesity risk.

Assessment of early vascular ageing (EVA) biomarkers may help refine risk assessment in obese individuals.

Practitioners may consider using EVA biomarkers for better risk assessment in obese patients.

The intervention group was more likely to achieve gestational weight gain (GWG) within recommendations compared to the control group (OR = 1.51; 95% CI (0.81, 2.80)).

Practitioners may consider structured nutrition and exercise interventions to help pregnant women achieve recommended weight gain.

The relative intervention effects were similar across different baseline body mass index, age, and sex groups.

The intervention may be effective for diverse populations with type 2 diabetes and obesity.

Individuals with lower levels of multimorbidity index scores at baseline experienced greater relative intervention effects.

Targeting interventions to individuals with lower baseline multimorbidity may enhance effectiveness.

Most societies endorse GLP-1RA therapy in patients with established or high risk of CVD independently of glycaemia.

Clinicians should follow current guidelines endorsing GLP-1RA therapy for patients at high risk for CVD, regardless of their glycaemic control.

In the study, 8.7% of participants receiving GLP-1 RA had a cardiovascular event compared to 11.2% of those receiving placebo.

The data indicates a lower incidence of cardiovascular events with GLP-1 RA treatment.

Low energy flux may make it difficult for weight-reduced individuals to maintain energy balance.

Understanding the challenges of low energy flux can help practitioners develop better strategies for weight maintenance.

Energy intake from 22 to 36 weeks of gestation was significantly higher in high gainers (3,437±99 kcal per day) compared with low+ideal gainers (2,687±110, P<.001).

Practitioners should consider the significant differences in energy intake when advising pregnant women on weight gain.

Late breakfast time mediated the relationship between morningness–eveningness preference and BMI.

Adjusting breakfast timing may help in managing BMI for individuals with Type 2 diabetes.

Morning preference (CSM ≥ 45) was associated with earlier breakfast time and lower BMI by 0.37 kg/m².

Encouraging morning preference may lead to earlier breakfast and lower BMI in Type 2 diabetes patients.

The in-person group had significantly higher Healthy Eating Index scores than the online group (p < .05).

In-person health coaching may lead to better dietary outcomes compared to online coaching.

Online coaching may be equally effective as in-person methods.

Practitioners can consider online health coaching as a viable alternative to in-person coaching.

Non-adherence to Danish food-based dietary guidelines is associated with up to 43% increased all-cause mortality.

Practitioners should encourage adherence to dietary guidelines to reduce mortality risk.