Browse the evidence

The quality of macronutrient content is more important than quantity for glycemic control.

Focus on the quality of foods rather than just calorie counting in dietary plans.

Low glycemic carbohydrates and replacement of saturated fats with unsaturated fats are beneficial for glycemic control and CVD risk reduction.

Encourage the consumption of low glycemic foods and healthy fats in dietary recommendations.

Strength training can improve endurance performance.

Incorporating strength training may benefit endurance athletes.

The prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD) decreased from 82.6% to 30.4% after treatment with semaglutide.

Semaglutide may significantly improve liver health in patients with type 1 diabetes and MASLD.

Lifestyle intervention combined with older obesity medications is associated with approximately 5%-10% weight loss.

Combining lifestyle changes with medications can enhance weight loss outcomes for patients.

GLP-1 analogs have shown efficacy in improving weight loss and cardiovascular risk factors.

Practitioners may consider GLP-1 analogs as a treatment option for weight management in menopausal women.

Gewichtsreduktion senkt die Konversion eines Prädiabetes in einen Typ-2-Diabetes um 58 % durch Lebensstilintervention.

Praktiker sollten Lebensstilinterventionen zur Gewichtsreduktion empfehlen, um das Risiko für Typ-2-Diabetes zu senken.

Eine Gewichtsreduktion von 10 kg senkt die Gesamtmortalität bei Menschen mit Typ-2-Diabetes um 25 %.

Gewichtsreduktion sollte als Strategie zur Verbesserung der Lebensdauer bei Diabetikern gefördert werden.

Eine Gewichtsreduktion verbessert Blutzuckerwerte und nahezu alle Komorbiditäten des Diabetes.

Ärzte sollten Gewichtsreduktion als Teil der Behandlung von Diabetes und seinen Komorbiditäten empfehlen.

Lifestyle modification can provide glycemic benefits to prevent type 2 diabetes (T2D) and its comorbidities.

Practitioners should encourage lifestyle modifications as a standard approach to prevent T2D.

Soy isoflavones can significantly contribute to lowering metabolic risk and affect hormonal balance in women with PCOS.

Incorporating soy isoflavones may be beneficial for women with PCOS in managing metabolic and hormonal issues.

All patients had complete diabetes remission at 12 months, maintained at 24 months.

Laparoscopic sleeve gastrectomy can lead to significant diabetes remission in obese patients, which is important for treatment planning.

Weight-reducing anti-diabetic agents and anti-obesity medications can effectively address both obesity and type 2 diabetes mellitus (T2DM).

Practitioners should consider using these combined strategies for better management of patients with obesity and T2DM.

Utilizing a combination of weight-reducing anti-diabetic agents, anti-obesity medications, and surgical procedures can lead to better clinical outcomes in patients with obesity and T2DM.

Combining different treatment modalities may enhance patient outcomes in managing obesity and T2DM.

The intervention resulted in a decrease in body weight, body mass index, waist circumference, blood pressure, and lipid metabolism parameters.

Health professionals can expect improvements in key health metrics when implementing similar interventions.

Short-term consumption of high-fat, low-carbohydrate diets combined with daily physical activity can dramatically alter patterns of fuel utilization and exercise responses.

Practitioners should consider incorporating HFLC diets with physical activity to enhance fuel utilization and exercise performance.

HFLC diets interact with endurance training to modulate both acute and chronic responses to exercise.

Endurance athletes may benefit from dietary strategies that include HFLC diets to optimize training responses.

Fat-adaptation protocols can enhance performance for certain individual athletes.

Exercise physiologists and sport nutritionists should consider fat-adaptation strategies for athletes who may benefit from them.

A 5-day high-fat diet followed by 1-day carbohydrate restoration resulted in a 45% increase in fat oxidation and a 30% decrease in carbohydrate oxidation during cycling at 70% VO2 peak.

Practitioners should consider the impact of high-fat diets on fat and carbohydrate metabolism during endurance activities.

Performance in a subsequent time-trial improved by 8% for the FAT diet compared to the CHO diet.

Competitive cyclists may achieve better performance by incorporating fat adaptation strategies.

A 5-day high-fat diet followed by 1-day carbohydrate restoration resulted in a 45% increase in fat oxidation and a 30% decrease in carbohydrate oxidation during cycling at 70% VO2 peak.

Cyclists may benefit from high-fat diets for improved fat oxidation during endurance activities.

Selecting carbohydrate sources to reduce dietary glycemic index (GI) is a promising weight management strategy.

Clinicians may consider recommending lower GI carbohydrate sources to help manage weight in obese patients.

GLP-1RAs promote weight loss and improve metabolic health.

GLP-1RAs can be utilized to aid in weight management and metabolic health improvement.

The combination of Cinnamomum cassia (300 mg) and Withania somnifera (150 mg) induced significant weight loss compared to placebo (−2.66% vs. −1.28%, respectively; p = 0.0002).

Practitioners may consider this combination as a low-cost supplement option for enhancing weight loss in overweight and obese patients.