Browse the evidence

Well-trained males and females can accurately gauge intraset rating of perceived exertion (RPE) during moderate repetition sets on the front squat and hexagonal bar deadlift.

Trainers can rely on RPE as a valid measure of exertion for their clients during these exercises.

The difference between actual and predicted repetitions performed (RPE difference) is significantly lower at a called RPE of 9 compared to 6 in both exercises.

Understanding RPE can help in predicting performance during training.

Significant inverse relationships exist between RPE and average concentric velocity (ACV) during both exercises.

Coaches can use RPE to adjust training intensity based on velocity metrics.

Ultra-processed foods are sold in portions up to 5 times larger than when first introduced.

This highlights the need for awareness regarding the increasing portion sizes of ultra-processed foods.

A greater intake of plant fat is associated with a lower risk for overall mortality (HRs, 0.91) and cardiovascular disease (CVD) mortality (HRs, 0.86), particularly from grains and vegetable oils.

Encouraging higher plant fat intake, especially from grains and oils, may benefit longevity.

A higher intake of total animal fat is associated with an increased risk for overall mortality (HRs, 1.16) and CVD mortality (HRs, 1.14).

Reducing animal fat intake may lower mortality risk.

Retatrutide (LY3437943) is relatively safe and supports once-weekly dosing.

Practitioners can consider retatrutide as a potentially safe option for treatment with a convenient dosing schedule.

Retatrutide may be superior to dulaglutide in reducing plasma glucose and body weight.

Practitioners may consider retatrutide as a potentially more effective option than dulaglutide for managing diabetes.

Pharmacologic interventions targeting modifiable cardiometabolic risk factors are a reasonable strategy to prevent CVD development and progression of MASLD.

Practitioners should consider pharmacologic interventions for patients with MASLD to mitigate CVD risk.

Resmetirom has shown positive effects regarding CVD risk in the context of MASLD treatment.

Consider resmetirom as a potential treatment option for patients with MASLD at risk for CVD.

Changes in HbA1c were related significantly to changes in weight, but not to changes in REM-AHI and NREM-AHI.

Weight management is crucial for improving glycaemic control in this population.

Mean total daily energy expenditure (TEE) for female soccer players was 2693 ± 432 kcal·d-1 over 12 days.

Practitioners should consider these energy expenditure values when planning nutrition for female soccer players.

88% of players were categorized with low energy availability (EA) status according to the threshold of <30 kcal·kg-1 FFM.

Practitioners should address low EA in training and nutrition strategies for female soccer players.

Mean daily carbohydrate intake was 3.3 ± 0.7 g·kg-1 body mass.

Practitioners should ensure adequate carbohydrate intake for performance in female soccer players.

The degree of capillarization in muscle is associated with the change in type II fiber CSA following resistance training.

Improving muscle capillarization may enhance the effectiveness of resistance training.

Significant decreases in peak velocity and mean velocity were found at 55% 1RM and 65% 1RM (p = 0.027 and p = 0.012 for peak velocity; p = 0.047 and p = 0.022 for mean velocity).

Trainers should be aware that velocity may decrease at certain loads during high-load training.

Obesity is a significant predisposing factor for heart failure with preserved ejection fraction (HFpEF).

Practitioners should consider obesity as a critical factor in managing patients with HFpEF.

Semaglutide treatment resulted in a 17% reduction in new-onset atrial fibrillation (AF) incidence compared to controls.

Semaglutide may be an effective treatment option for reducing the risk of new-onset AF in patients.

In trials without SGLT2 inhibitors, there was a significant reduction of 21% in new-onset AF.

Semaglutide may be more effective in reducing AF risk when not used with SGLT2 inhibitors.

Approximately 70% of participants could be accurately classified as with or without recurrent binge eating.

Practitioners can use this classification accuracy to identify individuals at risk for recurrent binge eating.

Intuitive eating emerged as the most important classifier of recurrent binge eating.

Encouraging intuitive eating may help reduce the risk of recurrent binge eating.

In most existing algorithms for calculating prandial insulin doses in type 1 diabetes, only carbohydrates are counted.

Current algorithms may need to be revised to include more than just carbohydrate counting.

In type 2 diabetes, the meal content is often not taken into consideration when calculating prandial insulin doses.

Practitioners should consider meal content when determining insulin doses for type 2 diabetes.

Chronic nutritional carbohydrate overload has disruptive metabolic effects and detrimental health consequences.

Reducing carbohydrate intake may improve metabolic health.