Browse the evidence

Specific population interventions can effectively improve diet and may be cost-effective.

Implementing targeted dietary interventions can lead to better health outcomes and may save costs.

Selected policy interventions may reduce health disparities.

Policymakers should consider dietary interventions as a means to promote health equity.

Maintainers lost weight mainly by themselves, while more regainers consulted with a dietitian.

Practitioners may consider encouraging self-directed weight loss strategies for better maintenance outcomes.

Current pharmacotherapy options for obesity include agents like liraglutide, semaglutide, and tirzepatide.

Practitioners should be aware of these specific pharmacotherapy options for treating obesity.

Novel therapies, including dual and triple incretin agonists, are under investigation for obesity treatment.

Practitioners should stay informed about emerging therapies that may enhance obesity treatment.

Bariatric surgery before liver transplantation is feasible and can improve liver function for patients on the transplant waiting list.

Bariatric surgery may be a beneficial option for patients with obesity awaiting liver transplantation to enhance liver function.

The consensus defines sarcopenic obesity with a 3-step algorithm, including screening, diagnosis, and intervention.

Practitioners can use this algorithm for diagnosing and managing sarcopenic obesity.

Certain metabolic and comorbid conditions disproportionately affect women.

Practitioners should consider gender-specific factors in obesity management.

Multidomain lifestyle intervention may slow biological aging long term, as captured by an FI-E.

Practitioners may consider recommending multidomain lifestyle interventions to promote long-term health benefits.

FI-E scores were relatively lower among lifestyle participants throughout follow-up.

Lifestyle interventions may be effective in reducing frailty over time.

Male participants experienced greater effects than females (P < 0.001).

Practitioners should consider gender differences when designing resistance training programs.

Tirzepatide was evaluated for its effects on cardiovascular and diabetic kidney disease biomarkers in overweight and obese adults with type 1 diabetes over a period of 21 months.

Practitioners may consider tirzepatide for managing cardiovascular and kidney health in overweight and obese patients with type 1 diabetes.

Maximal voluntary contraction (MVC) of the knee extensors was significantly greater in younger adults (256 ± 72 N·m) compared to older adults (137 ± 48 N·m), P < 0.001.

Younger adults demonstrate greater knee extensor strength, which may influence exercise programming for older adults.

Relative quadriceps muscle EMG activity was significantly higher in older adults compared to younger adults across all exercise tasks (P < 0.01).

Older adults may require different training approaches to optimize muscle activation.

A tendency toward a greater increase in fat-free mass (FFM) was observed in the OC group (3.7 ± 3.8%) compared to nonusers (2.7 ± 3.5%), with p = 0.08.

There may be a slight advantage in fat-free mass gain for OC users, warranting further investigation.

Strength gains are stimulated through a sequence of events including maximal mental effort and neural activation.

Emphasize mental effort and neural activation in training programs to enhance strength gains.

The intake of dairy appears to have a protective effect on some cardiovascular risk factors, or it is not worse than other SFA sources.

Incorporating dairy may be beneficial for cardiovascular health compared to other saturated fats.

Dairy products seem to present a different effect on cardiometabolic risk factors than other fat sources.

Understanding the unique effects of dairy can inform dietary recommendations regarding fat sources.

The study evaluated three test diets differing in carbohydrate-to-fat ratio during weight-loss maintenance over 20 weeks.

Dietary composition may play a significant role in maintaining weight loss.

The primary outcome measured was total energy expenditure using doubly-labeled water methodology.

Understanding total energy expenditure can help in designing effective weight maintenance strategies.

Secondary outcomes included resting energy expenditure, physical activity, and chronic disease risk factors.

Monitoring these secondary outcomes can provide insights into the effectiveness of dietary interventions.

The global increase in the consumption of low-nutrition products is associated with global increases in obesity and its associated diseases.

Practitioners should be aware of the impact of low-nutrition products on obesity trends.

Once semaglutide is stopped, people regain most of their pretreatment weight.

Practitioners should inform patients about the potential for weight regain after stopping treatment.

Dietary intake of trans fatty acids, palmitic acid, stearic acid, and saturated fatty acids from meat and unprocessed meat was modestly associated with a higher risk of coronary events.

Reducing intake of certain fatty acids may be beneficial for lowering coronary event risk.