16,558 findings · published 2017+
- CellularStrong
Changes in muscle density over time might precede adverse outcomes such as falls and fractures.
Practitioners should monitor muscle density as a potential indicator of future health risks.
Qualifies 2022 - NeuralStrong
Patients with persistent complete concentric velopharyngeal collapse in the supine position had a mean apnea–hypopnea index (AHI) of 54.7 events/h, significantly higher than the 60 patients without such collapse in position 4, who had a mean AHI of 35.5 events/h.
Clinicians should consider the severity of velopharyngeal collapse when assessing sleep apnea treatment options.
Supports 2023 - CellularStrong
The degree of velum and tongue base obstruction was significantly associated with sleep apnea severity in positions 2, 3, and 4 after adjusting for age, BMI, tonsil size, and tongue position.
Understanding the specific obstructions can guide targeted treatments for sleep apnea.
Supports 2023 - NeuralStrong
The study demonstrated the feasibility, safety, and usefulness of using a simple edge‐to‐edge, reusable oral appliance in drug-induced sleep endoscopy.
Oral appliances may be a viable option for patients undergoing sleep apnea evaluation.
Supports 2023 - CellularStrong
Sodium-glucose cotransporter 2 (SGLT2) inhibitors provide cardiovascular and renal protection in patients with type 2 diabetes mellitus (T2DM).
Practitioners should consider SGLT2 inhibitors as a treatment option for cardiovascular and renal protection in T2DM patients.
Supports 2018 - MolecularStrong
Conventional antihyperglycemic medications have minimal effect on lowering cardiovascular risk in T2DM patients.
Practitioners should be aware that conventional medications may not effectively reduce cardiovascular risk in T2DM patients.
Supports 2018 - Energy balanceStrong
Exploration of variation in responses to interventions can enhance understanding of generalizability of effects.
Practitioners should explore variation in responses to improve the applicability of their findings.
Supports 2022 - Energy balanceStrong
Powerlifting does not seem to affect shoulder, hip, or knee range of motion differently than recreational resistance training in women.
Practitioners can consider that powerlifting does not limit joint range of motion compared to general resistance training.
Refutes 2021 - Energy balanceStrong
Single-joint range of motion was not an effective predictor of strength in female powerlifters.
Strength training programs may not need to focus on improving ROM as a means to enhance strength in female powerlifters.
Refutes 2021 - Metabolic adaptationStrong
Obese class III (OCIII) insulin users incur the greatest annual healthcare expenditures among the studied population.
Targeted interventions may be beneficial for OCIII insulin users to manage healthcare costs.
Supports 2019 - MolecularStrong
Higher concentration of nicotinamide phosphoribosyltransferase (NAMPT) protein is associated with faster phosphocreatine (PCr) resynthesis.
Increasing NAMPT levels may enhance muscle recovery rates post-exercise.
Supports 2020 - MolecularStrong
31P-MRS based PCr resynthesis may represent a valid non-invasive surrogate marker of mitochondrial NAMPT in human skeletal muscle.
31P-MRS can be used as a non-invasive method to assess mitochondrial health in muscle.
Supports 2020 - CellularStrong
Polymeric biomaterials can mimic gastric bypass by blocking excessive absorption.
Practitioners may explore less invasive methods for obesity treatment using polymeric biomaterials.
Supports 2023 - HormonalStrong
Bioactive compounds influence appetite through multiple pathways.
Practitioners should consider the role of bioactive compounds in appetite regulation.
Supports 2024 - HormonalStrong
The melanocortin system is regulated by long-term and short-term regulatory hormones and nutrients.
Understanding the regulation of the melanocortin system can aid in appetite management strategies.
Supports 2024 - NeuralStrong
Bioactive compounds affect appetite regulation through the central nervous system, peripheral hormones, and intestinal microbiota.
Practitioners should consider multiple pathways when addressing appetite regulation.
Supports 2024 - CellularStrong
Understanding novel mutations in POMC and MC4R/MC3R may help identify strategies for the treatment and diagnosis of obesity, particularly childhood obesity.
This knowledge can guide interventions for childhood obesity.
Supports 2025New - Energy balanceStrong
Metabolically healthy individuals experienced lower event rates with increasing body mass index (BMI).
Emphasizing metabolic health may lead to better outcomes even in individuals with higher BMI.
Supports 2025New - HormonalStrong
Greater total testosterone levels were associated with better verbal fluency in men.
Practitioners may consider that higher testosterone levels could enhance verbal fluency in men with T2DM.
Supports 2022 - Energy balanceStrong
The literature on minimalist footwear presents inconsistent recommendations.
Clinicians should be cautious when recommending minimalist footwear due to inconsistent evidence.
Qualifies 2021 - Energy balanceStrong
The article aims to identify ideal clients for transitioning to minimalist running.
Understanding ideal candidates for minimalist footwear can help tailor recommendations.
Supports 2021 - Metabolic adaptationStrong
Psychotropic medications, especially antipsychotics, cause weight gain in individuals with severe mental illness (SMI).
Practitioners should be aware of the weight gain side effects of antipsychotic medications in SMI patients.
Supports 2023 - Metabolic adaptationStrong
Metformin and topiramate are commonly prescribed for weight gain in individuals with SMI, but their weight loss potential is modest.
Practitioners should consider the limited effectiveness of metformin and topiramate for weight management in SMI patients.
Qualifies 2023 - Metabolic adaptationStrong
The positive effects of the training program disappeared after 6 years.
Long-term benefits of short exercise programs may require ongoing engagement.
Refutes 2018