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A substantial increase of habitual protein intake above the currently recommended levels is achievable within 17 weeks in community-dwelling older adults.

Practitioners can encourage older adults to increase protein intake significantly above current recommendations.

Body fat mass initially increased, while skeletal muscle mass decreased, but this trend was reversed in the high protein group after resistance training.

Practitioners should note the potential for changes in body composition with high protein intake and resistance training.

The dual agonist tirzepatide has shown enhanced potency for weight loss compared to conventional GLP-1 mono agonist.

Practitioners may consider tirzepatide as a more effective option for weight loss in obese patients.

GLP-1 agonists reduce food intake and delay gastric emptying, contributing to weight loss.

Understanding these mechanisms can help practitioners better utilize GLP-1 agonists in treatment.

Glucagon coagonists like survodutide and mazdutide have demonstrated significant weight loss and improved glycemic control.

These agents may be effective options for patients needing weight loss and glycemic control.

The estimated load at 0 velocity (LD0) was predictive of 1 repetition maximum (1RM), explaining 70.2% of its variance.

LD0 can be used as a reliable predictor for assessing 1RM in training settings.

Combining the slope of the individual load-velocity profile (LVP) with LD0 increased the prediction power of 1RM to 84.4%.

Incorporating the slope of the LVP can enhance the accuracy of 1RM predictions in training.

GLP-1 receptor agonists produce significant weight loss.

Practitioners can consider GLP-1 receptor agonists as a viable option for weight loss in patients with obesity.

Regular exercise promotes, maintains, and restores healthy functioning of nearly every physiological system of the human body.

Practitioners should encourage regular exercise as a key component of health maintenance.

Protein supplementation after exercise improves fat-free mass by 0.54 kg and skeletal muscle mass by 0.34 kg compared to placebo.

Practitioners should recommend protein supplementation after exercise to enhance muscle mass.

Protein supplementation at night improves handgrip strength by 2.85 kg and leg press strength by 12.12 kg compared to placebo.

Practitioners should consider recommending protein supplementation at night to improve strength.

Milk proteins, red meat, and mixed protein are effective for gains in both muscle mass and strength.

Practitioners should prioritize milk proteins and red meat in dietary recommendations for muscle gain.

Whey protein supplementation resulted in a greater increase in vastus lateralis muscle thickness (8.4 ± 2.5%) compared to leucine-matched collagen peptides (5.6 ± 2.6%) after a 10-week resistance training program.

Practitioners should consider whey protein as a more effective supplement for increasing muscle thickness in untrained individuals.

Whey protein supplementation led to a greater increase in biceps brachii muscle thickness (10.1 ± 3.8%) compared to leucine-matched collagen peptides (6.0 ± 3.2%) after a 10-week resistance training program.

Whey protein may be more effective than collagen peptides for increasing biceps muscle size in untrained individuals.

There was a similar increase in muscle performance (peak torque, mean power output, and peak power output) between whey protein and leucine-matched collagen peptides groups after the resistance training program.

Both whey protein and collagen peptides can enhance muscle performance similarly in untrained individuals.

Sustained improvements were noted in body mass (-7.6 %), HbA1c (-0.3 %), triglycerides (-18.4 %), HDL-C (+17.4 %), and inflammatory markers.

Practitioners can expect significant improvements in metabolic health markers with this dietary approach.

GLP-1 receptor agonists (GLP-1RAs) have proven efficacy in glucoregulation and weight loss.

Practitioners can consider GLP-1RAs as effective treatment options for managing diabetes and obesity.

Tirzepatide facilitated unprecedented weight loss of up to 22.5% in non-diabetic individuals living with obesity.

This indicates that tirzepatide can be a significant option for weight management in obese individuals.

Tirzepatide provides glycemic lowering and weight loss effects.

Tirzepatide may be effective for patients needing to lower blood sugar and lose weight.

Exercise is a first-line prevention and intervention strategy for type 2 diabetes.

Practitioners should prioritize exercise as a key component in diabetes prevention and treatment.

GLP-1 receptor agonists decrease weight in people with schizophrenia.

GLP-1 receptor agonists may be considered as a treatment option for weight management in patients with schizophrenia.

Physical activity should be included in medical treatments for excess weight and adiposity as deemed medically appropriate.

Practitioners should incorporate physical activity into treatment plans for patients with excess weight.

For weight loss and prevention of weight gain, physical activity should be progressed to at least 150 min·wk −1 of moderate-intensity.

Encourage clients to engage in at least 150 minutes of moderate-intensity physical activity weekly for effective weight management.

Excess accumulation of visceral adipose tissue (VAT) leads to the clustering of cardiometabolic risk factors.

Reducing visceral fat may help mitigate cardiometabolic risks.