Browse the evidence

Future studies investigating the long-term effects of chronic high protein intake on bone tissue health are warranted.

Practitioners should consider the need for ongoing research into the long-term impacts of high protein diets on bone health.

A 10% energy surplus did not result in a significant change in body protein mass (0.00 kg; 95% CI, -0.38-0.39 kg; P = 0.980).

A modest increase in energy intake may not be sufficient to promote body protein mass gain.

Protein supplementation does not seem to provide further improvements in untrained and healthy subjects.

Practitioners should consider the training status of individuals when recommending protein supplementation.

Non-responders to the PF regimen demonstrated only transient and limited metabolic shifts.

Understanding the differences in metabolic responses can guide dietary strategies for T2D management.

A prescrição de suplementação alimentar nem sempre é realizada com orientação correta por profissionais adequados.

É crucial que a suplementação seja orientada por nutricionistas para evitar riscos à saúde.

Mitochondrial dysfunction plays a pivotal role in the onset and progression of diabetes.

Understanding mitochondrial dysfunction can guide therapeutic strategies for diabetes management.

Innovative therapeutic strategies are needed to address mitochondrial dysfunction in diabetes.

Practitioners should consider new therapies targeting mitochondrial function in diabetes care.

The prevalence of any remission in the plate model was 27.1% during the first 2 years, decreasing over time.

The plate model may initially improve diabetes remission rates, but these rates decline over time.

Intensive modulation of glycemia and blood pressure has proven disappointing in preventing cardiovascular events.

Clinicians should reconsider reliance on glycemic and blood pressure control alone for cardiovascular risk reduction.

Elevated LDL-cholesterol reflects an imbalance in food energy intake and expenditure.

Practitioners should consider energy balance when addressing LDL-cholesterol levels.

Circulating cholesterol levels predict risk of coronary heart disease (CHD) death only to the degree that pro-inflammatory highly unsaturated fatty acids exceed less-inflammatory HUFA.

Understanding the type of dietary fats consumed is crucial for assessing heart disease risk.

A shift towards reduced carbohydrate intake and increased dietary fat may be linked to higher morbidity and mortality rates in patients with diabetes.

Practitioners should consider the implications of dietary fat and carbohydrate ratios in diabetes management.

The majority of animal studies demonstrated a greater impact from high-fat diets compared with higher-sugar diets.

Animal studies suggest that high-fat diets may pose greater risks than high-sugar diets, informing dietary recommendations.

Counselors spent less time providing feedback on participant self-monitoring data over the course of the study, decreasing from a mean of 53 minutes to 26 minutes.

Counselors can improve efficiency in providing feedback over time, which may reduce costs in technology-based weight loss interventions.

Counselors may be increasing their efficiency in providing feedback over time.

Counselors should focus on developing skills that enhance feedback efficiency over time.

A plant-based diet is associated with an increased risk of higher TyG in women (OR = 1.25 for PDI and OR = 1.55 for hPDI).

Practitioners should be cautious about recommending high plant-based diets for women without considering overall dietary balance.

People in Northern China often consume more plant-based foods.

Understanding local dietary habits can inform nutritional guidance and interventions.

The study will carry out meta-regression to determine the influence of moderator variables on findings.

Understanding moderator variables can help tailor training programs more effectively.

At the lowest income level, the proportions of individuals in the best carbohydrate quality category reduced from 26.9% to 20.6%.

Practitioners should be aware that lower income is associated with reduced dietary quality in carbohydrates.

At the highest income level, the proportions of individuals in the best carbohydrate quality category increased from 22.9% to 26.6%.

Practitioners should recognize that higher income is associated with improved dietary quality in carbohydrates.

Different eccentric phase tempos do not produce significant differences in strength and muscle hypertrophy for knee extensors, except for the Vastus Medialis.

Practitioners may not need to vary eccentric tempos for hypertrophy and strength gains in knee extensors, except for targeting the Vastus Medialis.

There were no significant differences in myofibrillar or sarcoplasmic protein concentrations between high and low anabolic responders before or after the 12-week RET program.

Practitioners should note that muscle protein concentrations may not be a reliable indicator of anabolic response to resistance training.

Training age was not related to RIR accuracy close to failure (i.e., 9RPE).

RPE assessments at high exertion levels may be consistent regardless of training experience.

Total repetitions per set do not seem to affect RIR accuracy when close to failure (i.e. 9RPE).

When training close to failure, perceived exertion ratings may be more reliable regardless of total repetitions.