Browse the evidence

Non-nutritive sweeteners (NNS) may support energy intake reduction and promote glycemic control and weight management when substituted for added sugars.

Practitioners may consider recommending NNS as a strategy to reduce added sugar intake.

Plant-based diets with healthful complex carbohydrates reduced cardiovascular disease (CVD).

Encourage patients to adopt plant-based diets with complex carbohydrates to lower CVD risk.

High-dose omega-3 fatty acids lower triglycerides, reduce CVD, and prevent coronary plaque progression.

Consider recommending high-dose omega-3 supplements for patients at risk of CVD.

Individuals should minimize saturated fats and refined carbohydrates, eliminate trans-fat, and increase fruits, vegetables, whole grains, low-fat dairy, and fish or other omega-3 fatty acids.

Advise patients to follow these dietary guidelines to improve heart health.

Multiple risk factors should be targeted simultaneously in T2DM patients to reduce CV events.

A comprehensive approach addressing multiple risk factors is essential for effective cardiovascular disease prevention in T2DM patients.

The long-lever posterior-tilt plank displayed a significantly increased activation of the upper rectus abdominis, lower abdominal stabilizers, and external oblique compared to the traditional prone plank.

Incorporating the long-lever posterior-tilt plank may enhance core muscle training effectiveness.

The long-lever plank showed significantly greater activity compared to the traditional plank in the upper rectus abdominis and lower abdominal stabilizers.

Using the long-lever plank can specifically target the upper rectus abdominis and lower abdominal stabilizers more effectively.

The posterior tilt plank elicited greater activity in the external oblique compared to the traditional plank.

The posterior tilt plank can be beneficial for targeting the external oblique during core workouts.

Dietary protein recommendations for older adults should be increased to mitigate age-related decline in skeletal muscle.

Practitioners should consider recommending higher protein intake for older adults to support muscle health.

Alternative protein sources may support muscle anabolism in active older adults.

Practitioners should explore alternative protein sources for their potential benefits in older adults.

Tirzepatide treatment significantly reduced the 10-year predicted risk of developing type 2 diabetes compared with placebo in participants with obesity or overweight.

Practitioners can consider tirzepatide as an effective intervention for reducing diabetes risk in overweight or obese patients.

At week 72, mean absolute T2D predicted risk score reductions were significantly greater in tirzepatide groups (5 mg, 12.4%; 10 mg, 14.4%; 15 mg, 14.7%) versus placebo (0.7%).

The specific dose of tirzepatide can be tailored to achieve greater reductions in diabetes risk.

For participants with and without prediabetes, risk reductions were significantly greater in tirzepatide groups versus placebo.

Tirzepatide may be beneficial for a broader range of patients, including those with prediabetes.

Bariatric surgery leads to a higher remission rate for type 2 diabetes mellitus than non-surgical treatment.

Bariatric surgery should be considered for patients with type 2 diabetes who are not achieving remission through non-surgical methods.

Fat-free mass normalized to height is a statistically predictive determinant of maximum parallel barbell back squat strength.

Practitioners should focus on increasing fat-free mass to enhance barbell back squat strength.

Varying exercise selection can influence muscle hypertrophy and strength gains.

Fitness professionals should consider incorporating a variety of resistance exercises to enhance muscle growth and strength.

Systematic variation in exercise selection enhances regional hypertrophic adaptations and maximizes dynamic strength.

Implementing a structured variation in resistance exercises can lead to better muscle development and strength outcomes.

Excessive, random variation in exercise selection may compromise muscular gains.

Avoid excessive changes in exercise selection to maintain optimal muscle growth and strength.

Exercise and diet are effective low-cost treatment options for controlling hyperglycemic episodes in patients with type 2 diabetes.

Practitioners should consider incorporating exercise and dietary changes as primary strategies for managing blood sugar levels in diabetic patients.

A single bout of either resistance or endurance exercise reduces the prevalence and duration of hyperglycemic excursions in patients with type 2 diabetes.

Encouraging patients to engage in both resistance and endurance exercise can help manage their blood sugar levels effectively.

Diets containing high-GI carbohydrates are independent risk factors for type 2 diabetes onset.

Advising patients to limit high-GI carbohydrate intake may reduce their risk of developing type 2 diabetes.

BFR training is an effective alternative for increasing muscle CSA in older men.

Practitioners can consider BFR training as a viable method to enhance muscle growth in older male populations.

Excess body weight is a significant risk factor for breast cancer and increases the risk of therapy-related morbidity, recurrence, and breast cancer-related mortality.

Healthcare providers should prioritize weight management in breast cancer patients and survivors.

Cancer guidelines recommend that overweight or obese breast cancer survivors lose weight and that those with a normal BMI maintain stable body weight.

Practitioners should follow cancer guidelines for weight management in breast cancer survivors.