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Higher protein consumption was more effective for weight stability in both sexes, with better results in obese women.

Practitioners should consider recommending higher protein diets for weight maintenance, especially in obese women.

The reported dietary benefits for weight sustainability should be ascribed to the macronutrient distribution (higher protein diets) rather than to the structured mode of delivery.

Focus on macronutrient distribution, particularly protein intake, for effective weight maintenance strategies.

Cumulative average total moderate-to-vigorous physical activity (MVPA) is inversely associated with progression to chronic kidney disease (CKD), with a hazard ratio (HR) of 0.91 per 100 min/week higher amount.

Increasing moderate-to-vigorous physical activity may help reduce the risk of chronic kidney disease in individuals with type 2 diabetes and obesity.

An increase in total MVPA from baseline to year 4 (≥63.2 min/week) is associated with a 33% lower risk of progression to CKD compared to the largest MVPA reduction (<−198.3 min/week).

Encouraging increases in physical activity can significantly lower the risk of chronic kidney disease in this population.

Increases in MVPA accumulated in bouts of both <10 min and ≥10 min are associated with a lower risk of progression to CKD.

Incorporating both short and longer physical activity bouts can be beneficial for reducing CKD risk.

Participants in the weight loss program experienced a significant reduction in weight of -4.8±2.3 kg.

Weight loss programs can be effective for first responders with obesity.

Participants showed a significant reduction in percent body fat of -3.9±1.7%.

Effective weight loss programs can also lead to reductions in body fat.

The weight loss program is feasible for supporting career firefighters in their weight loss efforts.

Programs utilizing technology and coaching can effectively aid weight loss in first responders.

Low-carbohydrate diets are effective in reversing metabolic syndrome, with 1580 respondents reporting decreased waist circumference and weight, increased energy levels, and decreased hunger.

Practitioners may consider recommending low-carbohydrate diets for patients with metabolic syndrome.

A promising strategy to increase physical activity is to encourage people to walk more, starting small and increasing gradually over time.

Starting with small walking goals can help individuals increase their physical activity sustainably.

Substitution of low- and no-calorie sweetened beverages (LNCSBs) for sugar-sweetened beverages (SSBs) was associated with a reduction in body weight by 1.06 kg (95% CI, -1.71 to -0.41 kg).

Practitioners may consider recommending LNCSBs as a substitute for SSBs to aid in weight management.

Substituting LNCSBs for SSBs was associated with a reduction in body mass index (BMI) by 0.32 (95% CI, -0.58 to -0.07).

Practitioners may use BMI changes as an additional metric for assessing the effectiveness of LNCSBs in dietary interventions.

Postintervention weight change averaged -3.7 ± 9.5%, with greater weight loss in the DSE than the ILI group.

Practitioners should note that weight loss outcomes vary significantly between intervention types.

Diet is a prominent modifiable element driving weight gain and adiposity.

Practitioners should focus on dietary modifications to address obesity.

The intervention group achieved a mean body weight change of −9.5% (±4.1) with 90% of participants losing ≥ 5%.

Practitioners can consider remote interventions as effective for weight loss in older adults.

Initial adopters engaged in 108.3 minutes per week more at 1 year compared with early nonadopters (P < .01).

Encouraging early adoption of physical activity can lead to significantly higher activity levels over time.

Failure to achieve PA goals at 2, 3, or 4 months results in less overall PA at 1 year.

Identifying individuals who struggle with early PA goals can help target interventions.

Weight loss reduces the recurrence of symptomatic atrial fibrillation.

Weight management should be a focus in the treatment plan for patients with AF.

Oral semaglutide, 50 mg, led to a mean percentage change in body weight of -14.3% compared to -1.3% with placebo.

Oral semaglutide is effective for significant weight loss in this population.

84.3% of participants on semaglutide achieved a 5% or greater body weight reduction compared to 17.2% on placebo.

A high proportion of patients on semaglutide can expect significant weight loss.

R-ESG offered higher total body weight loss (TBWL%) than GLP1/GIP-RA at 3 months (11.2% vs. 4.3%, p < .001), 6 months (13.5% vs. 6.8%, p < .001), and 12 months (13.4% vs. 9.2%, p = .07).

Practitioners may consider R-ESG as a more effective option for weight loss in patients experiencing weight recidivism after sleeve gastrectomy.

GLP1/GIP-RA achieved significantly lower TBWL% in patients with prior SG compared to those with intact stomach at 3 months (4.3% vs. 5.7%, p = .02), 6 months (6.8% vs. 9.2%, p = .02), and 12 months (9.2% vs. 12.7%, p = .03).

Practitioners should be aware that GLP1/GIP-RA may be less effective for weight loss in patients with prior sleeve gastrectomy compared to those with intact stomachs.

In a medical weight loss program that used meal replacements to reduce calorie intake combined with weekly behavior change classes, weight loss was 16.2 kg and 14.4% for the 61% of all enrollees who completed 16 months of treatment.

Meal replacement diets combined with behavior change classes can lead to significant weight loss.

Over 2 years later, weight loss of 14.3 kg and 12.9% of initial weight persisted, and patients were not regaining their lost weight.

Patients can maintain significant weight loss long-term with this intervention.