Browse the evidence

Vegan dietary patterns can be healthy if followed very carefully with regard for potential nutritional deficiencies.

Practitioners should ensure that patients on vegan diets are aware of and manage potential nutritional deficiencies.

The likely beneficial effects of vegan dietary patterns on risk of cardiometabolic diseases and cancers are counterbalanced by the potential of such diets to be deficient in several important micronutrients.

Patients should be informed about both the benefits and potential nutritional risks of vegan diets.

LLM responses had significantly higher scores than internet responses in the 'objectivity' and 'reproducibility' categories.

Practitioners may consider using LLMs for more objective and reproducible information on GLP1RA therapy.

Current therapeutic strategies for obesity include lifestyle interventions, pharmacologic treatments, and bariatric surgery.

Practitioners should consider a multi-faceted approach to obesity treatment.

Both treatments did not negatively impact fat-free mass after 3 months.

Both treatments can be used without concern for loss of lean body mass.

Most individuals who lose weight through diet and lifestyle interventions regain all or a substantial portion of the weight back within 5 years.

Practitioners should be aware that weight loss may not be sustainable for many individuals.

Community-based lifestyle interventions to manage excess weight can be successfully conducted in Indigenous Australians, but with generally limited efficacy.

Practitioners should consider implementing community-based lifestyle programs, while being aware of their limited effectiveness.

The effect of lifestyle programs on weight reduction was modest (∼2-4 kg after 4-12 months).

Weight loss from lifestyle programs may be limited, and practitioners should set realistic expectations.

Tirzepatide achieves unprecedented weight loss, but case reports suggest potential sexual side effects.

Clinicians should monitor for potential sexual side effects in patients using Tirzepatide for weight loss.

Non-Hispanic Black (NHB) participants had lower percent total weight loss (%TWL) at 3, 12, and 24 months compared with Hispanic (H) and non-Hispanic White (NHW) participants.

Healthcare providers should consider racial and ethnic differences when evaluating weight loss outcomes post-surgery.

Tirzepatide produced meaningful weight loss across groups, but outcomes varied based on weight-reduction status and T2D status.

Practitioners should consider individual patient factors when prescribing tirzepatide for weight loss.

The S3 guideline for the prevention and treatment of obesity includes new recommendations on stigmatization, diagnostics, and therapy, incorporating areas like E-Health.

Practitioners should consider the new recommendations in their approach to obesity treatment.

The treatment of obesity is undergoing significant changes due to new weight-reducing medications, innovations in intervention, digital therapy options, and political decisions.

Practitioners should be aware of the evolving landscape of obesity treatment options.

There are no significant differences in muscle mass and strength gains between consuming protein three or five times a day.

Practitioners can advise that both three and five protein meals are effective for muscle gain.

Adherence to recommended dosage and seeking medical advice regarding possible side effects/interactions is recommended.

Practitioners should advise patients to follow dosage guidelines and consult healthcare providers.

Approximately 1-in-10 participants met the resistance training guidelines.

Only a small fraction of the population adheres to recommended resistance training guidelines.

The study will evaluate both quantitative and qualitative effects of the SALUD program.

The dual evaluation approach can provide comprehensive insights for T2DM interventions.

Metabolic bariatric surgery is associated with durable weight loss and lower observed rates of major adverse cardiovascular events (MACE), heart failure, and all-cause mortality compared with non-surgical care.

Practitioners can consider metabolic bariatric surgery as an effective option for achieving weight loss and reducing cardiovascular risks.

The incidence of using hypoglycemic drugs was 36.15% in the plate model compared to 75.54% in the low-fat model (P<0.001).

Implementing the plate model may significantly reduce the need for hypoglycemic medications in newly diagnosed type 2 diabetes patients.

A median SPAN score (52.8) was associated with a 41% lower risk of MACE (HR: 0.59; 95% CI: 0.49, 0.70).

Practitioners should aim for a balanced SPAN score to lower cardiovascular event risk.

This paper conducts a systematic review and meta-analysis of the effects of SIT/HIIT versus MICT on measures of body composition.

The findings may help practitioners understand the comparative effects of different training modalities on body composition.

The quality of lipids improved in women and among individuals reporting some away-from-home food consumption.

Practitioners should note that lipid quality may improve with certain consumption patterns, particularly in women.

Weight gain during pregnancy was significantly lower in the intervention group compared to the control group, with a reduction of 21%.

Resistance training may help limit excessive weight gain during pregnancy.

Men performed a higher weekly sets volume (WSV) for upper body muscles than women (47.2±14.6 vs. 18.2±7.4 sets).

Trainers should consider gender differences when designing upper body training programs.