Browse the evidence

Nutrient timing is a strategy for enhancing muscular adaptations and athletic performance.

Practitioners should consider nutrient timing as a potential strategy for improving muscle adaptations.

Higher carbohydrate intake was associated with lower CVD risk, with the lowest risk for quintile 3 (41.0%–44.3% energy as carbohydrate) versus quintile 1 (<37.1% energy as carbohydrate) (OR 0.56, 95% CI 0.35 to 0.91, p=0.02).

Practitioners may consider recommending moderate carbohydrate intake for reducing CVD risk in this population.

5-10% weight loss leads to significant improvement in glycemic control, lipids and blood pressure.

Weight loss of 5-10% should be targeted to improve health outcomes in patients with type 2 diabetes.

A weight-centric therapeutic approach is rational to improve glycemic and other metabolic outcomes in patients with T2DM.

Adopting a weight-centric approach can enhance treatment outcomes for T2DM patients.

Resistance-based exercise programs resulted in a significant change of +0.8 kg in lean mass (95% CI = 0.6 to 0.9 kg, P < 0.001).

Resistance training can effectively increase muscle mass in overweight and obese individuals.

Higher intake of dairy can decrease total cholesterol and reduce waist circumference and increase HDL cholesterol.

Encouraging higher dairy consumption may help improve cholesterol levels and waist circumference.

Sustained improvements were noted in body mass (-7.6 %), HbA1c (-0.3 %), triglycerides (-18.4 %), HDL-C (+17.4 %), and inflammatory markers.

Practitioners can expect significant improvements in metabolic health markers with this dietary approach.

Traditional ergo nutritional supplementation of carbohydrates and proteins combined improves recovery processes.

Incorporating carbohydrates and proteins in recovery nutrition is beneficial.

Consumption of low-carbohydrate, high-fat diets alters patterns of fuel utilization during endurance training.

Practitioners should consider low-carbohydrate, high-fat diets for athletes to optimize fuel utilization.

Fuel availability acts as a 'trigger' for adaptation in muscle during exercise.

Ensuring adequate fuel availability can enhance training adaptations in athletes.

Complete T2DM remission was achieved in 78.3%, 76.2%, and 71.4% at 1, 3, and ≥5 years respectively.

Bariatric surgery can lead to significant long-term remission of type 2 diabetes in obese patients.

Both liraglutide (3 mg) and naltrexone/bupropion (32/360 mg) improved body weight and composition, carbohydrate and lipid metabolism, and liver fat and function.

Practitioners can consider both liraglutide and naltrexone/bupropion as effective options for improving metabolic health in patients with obesity.

Nutritional intake guidelines can be individualized to target multiple long-term conditions.

Nutrition plans should be customized to address specific health conditions.

CLA supplementation is associated with increased muscle variables or decreased adiposity variables.

CLA may be beneficial for individuals looking to improve muscle mass or reduce fat.

Body composition improved with losses in fat mass and gains in overall proportion of lean muscle and skeletal muscle.

Practitioners can expect improvements in body composition with semaglutide treatment.

Advances in metabolic surgery, pharmacologic therapy, and lifestyle modification have made remission of diabetes more feasible.

Healthcare providers should consider these advancements when discussing treatment options.

Meal replacement (MR) significantly reduced glycated hemoglobin A1c (HbA1c) by -0.46%, fasting blood glucose (FBG) by -0.62 mmol/L, body weight by -2.43 kg, and body mass index (BMI) by -0.65 compared to conventional diabetic diets (CDs).

Implementing meal replacement strategies can lead to significant improvements in glycemic control and weight management for T2D patients.

Total meal replacement showed greater improvement in HbA1c, FBG, body weight, and BMI compared to partial meal replacement.

Total meal replacement may be more effective than partial meal replacement for improving health markers in T2D patients.

Evidence-based nutritional and lifestyle strategies are crucial for effective GLP-1 treatment.

Clinicians should integrate nutritional and lifestyle interventions to enhance GLP-1 treatment outcomes.

Resistance exercises seem to be beneficial for patients with type 1 diabetes.

Healthcare providers should consider recommending resistance training for patients with type 1 diabetes.

ADA/ISPAD goal achievement was associated with greater cardiopulmonary fitness, with VO2peak values significantly higher in those meeting more goals.

Practitioners should promote achieving ADA/ISPAD goals to enhance cardiopulmonary fitness in adolescents with type 1 diabetes.

Dietary energy intake and macronutrient ratios should be manipulated to optimize muscular adaptations.

Athletes should adjust their diet to enhance muscle growth effectively.

Weight loss can improve obesity-related comorbidities such as metabolic syndrome, diabetes, cardiovascular disease, and obstructive sleep apnea.

Weight loss should be emphasized in preoperative counseling for patients with obesity.

Diabetes remission occurred in five GB participants and no medical participants (relative risk 0.76, 95% CI: 0.55-0.93, p = .048).

GB surgery may increase the likelihood of diabetes remission in overweight individuals with type 2 diabetes.