471 findings · Metabolic adaptation · published 2022+
- Metabolic adaptationStrong
For the low-carbohydrate diet, race, body fat percentage, and fasting glucose at baseline are significant predictors of weight loss success.
Practitioners should consider these factors when recommending low-carbohydrate diets.
Supports 2022 - Metabolic adaptationStrong
Participants with higher sugar-sweetened beverages (SSBs) and artificially sweetened beverages (ASBs) intake and lower physical activity were independently at higher risk of type 2 diabetes (T2D).
Reducing intake of SSBs and ASBs while increasing physical activity may lower the risk of developing T2D.
Supports 2023 - Metabolic adaptationStrong
Participants who did not meet physical activity guidelines and consumed more than 2 servings/day of SSBs had a significantly higher risk of T2D compared to those who met physical activity guidelines and never/rarely consumed SSBs.
Encouraging adherence to physical activity guidelines is crucial, especially for those consuming high amounts of SSBs.
Supports 2023 - Metabolic adaptationStrong
Even among participants who met physical activity guidelines, those who consumed more than 2 servings/day of SSBs had a higher risk of T2D.
Limiting SSB intake is important for reducing T2D risk, even for those who are physically active.
Supports 2023 - Metabolic adaptationStrong
Twins on the healthy vegan diet had a greater reduction in LDL cholesterol after 8 weeks compared to those on the healthy omnivorous diet (-15.2 vs. -2.3 mg/dL).
A vegan diet may be more effective than an omnivorous diet for lowering LDL cholesterol.
Supports 2023 - Metabolic adaptationStrong
FDA-approved anti-obesity medications can facilitate weight loss and enhance metabolic indices.
Practitioners can recommend these medications for weight management in obese patients.
Supports 2023 - Metabolic adaptationStrong
The reduction of excess body fat is crucial for the treatment of type 2 diabetes.
Weight loss strategies should be prioritized in diabetes management plans.
Supports 2023 - Metabolic adaptationStrong
Obesity is a primary driver for the development of type 2 diabetes.
Weight loss interventions should be prioritized in managing patients with type 2 diabetes.
Supports 2024 - Metabolic adaptationStrong
Obesity is recognized as a chronic, progressive condition requiring early intervention and long-term management.
Practitioners should prioritize early intervention and long-term strategies in managing obesity.
Supports 2024 - Metabolic adaptationStrong
Pharmacotherapy is highly effective in reducing body weight and improving metabolic parameters.
Pharmacotherapy should be considered as a key component in obesity treatment plans.
Supports 2025New - Metabolic adaptationStrong
Baseline metabolic health predicts weight-loss outcomes and recurrence risk.
Assessing baseline metabolic health can guide individualized treatment plans for bariatric surgery patients.
Supports 2026New - Metabolic adaptationStrong
Tailored cardiac rehabilitation programs integrating individualized exercise, nutritional support, and pharmacotherapy show short-term benefits.
Implementing tailored CR programs can enhance short-term outcomes for obese patients.
Supports 2026New - Metabolic adaptationStrong
Incretin polyagonists significantly reduced body weight compared to placebo (MD -11.47; 95% CI: -14.00 to -8.95).
Incretin polyagonists can be considered effective for weight management in obese patients.
Supports 2026New - Metabolic adaptationStrong
Significant reductions were observed in waist circumference (MD -9.40; 95% CI: -11.91 to -6.89).
Incretin polyagonists may help reduce waist circumference in obese individuals.
Supports 2026New - Metabolic adaptationStrong
Precision nutrition may mitigate adverse effects and weight recovery during pharmacotherapy.
Incorporating precision nutrition can enhance the effectiveness of obesity treatments.
Supports 2026New - Metabolic adaptationStrong
Metabolic therapies like tirzepatide can reduce weight and improve OSA severity.
Incorporating metabolic therapies may enhance treatment strategies for patients with obesity and OSA.
Supports 2026New - Metabolic adaptationStrong
Protein ingestion increased circulating plasma amino acid concentrations.
Protein supplementation can effectively elevate amino acid levels in the bloodstream post-exercise.
Supports 2025New - Metabolic adaptationStrong
Resistance exercise (RE) significantly increased metabolic flexibility in older men compared to no exercise (NE), with a medium-to-large effect size.
Incorporating resistance exercise into routines can enhance metabolic flexibility in older adults.
Supports 2026New - Metabolic adaptationStrong
At 20 weeks, the protein group demonstrated greater improvement in the Short Physical Performance Battery and lower fat mass at 11 weeks.
Protein supplementation may lead to specific improvements in physical performance and fat loss in stroke patients.
Supports 2025New - Metabolic adaptationStrong
A high-protein diet increased daily protein intake to 1.6 g/kg body weight and resulted in significantly increased concentrations of two metabolites and reduced concentrations of 98 metabolites compared to baseline.
Practitioners can consider a high-protein diet as a viable option for older adults to enhance metabolic health.
Supports 2026New - Metabolic adaptationStrong
Post-exercise protein (PRO) intake exceeded current recommendations by 4.6-fold.
Athletes may be consuming excessive protein post-exercise, which could be adjusted based on recommendations.
Supports 2024 - Metabolic adaptationStrong
Adequate protein intake of approximately 1.6 g/kg/day is essential for supporting hypertrophy, with meal distribution of about 3-4 meals/day recommended.
Ensure protein intake is around 1.6 g/kg/day and distribute meals to support muscle growth.
Supports 2026New - Metabolic adaptationStrong
Time-efficient resistance training strategies such as supersets, drop sets, and rest-pause sets can preserve training volume and elicit similar muscular adaptations in less time than traditional training.
Practitioners can implement these time-efficient strategies to help clients maintain strength and hypertrophy despite time constraints.
Supports 2025New - Metabolic adaptationStrong
Weight loss and weight management in people with type 2 diabetes can alter the primary disease process of obesity.
Practitioners should consider weight loss strategies as a means to manage obesity in type 2 diabetes patients.
Supports 2024