Browse the evidence

Individuals with a low resting metabolic rate (RMR) for a given body size are at higher risk of significant weight gain, relative to those with a high RMR.

Practitioners should consider RMR when assessing weight gain risk in individuals.

Consumption of trans fatty acids (TFAs) should be virtually eliminated in the United Kingdom.

Practitioners should advocate for the reduction of TFAs in food products.

There is no known safe level of consumption of trans fatty acids.

Advise against any consumption of TFAs in dietary recommendations.

Resistance training can promote marked increases in skeletal muscle mass.

Resistance training is effective for increasing muscle mass, which practitioners can leverage in training programs.

For people with type 2 diabetes, an algorithm including lifestyle modification and anti-diabetic medications is suggested.

Health practitioners should implement lifestyle modifications and consider medication options for managing type 2 diabetes.

The lying leg curl (LLC) elicited significantly greater normalized mean activation of the lower lateral and lower medial hamstrings compared with the stiff-legged deadlift (SLDL) (p ≤ 0.05).

Practitioners may choose the lying leg curl to specifically target the lower hamstrings more effectively.

The study supports the notion that the hamstrings can be regionally targeted through exercise selection.

Exercise selection can be optimized to target specific regions of the hamstrings.

RIR predictions are more accurate when closer to failure, with RIRDIFF values of 2.05 ± 1.73 at 9RPE, 3.65 ± 2.46 at 7RPE, and 5.15 ± 2.92 at 5RPE.

Trainers should encourage clients to gauge their exertion levels closer to failure for more accurate RIR assessments.

Smartphones provide a unique platform to aid in the delivery of behavioral weight loss programs.

Practitioners can consider integrating smartphone applications into weight loss programs.

Most weight loss apps lack evidence-based behavior change strategies.

Practitioners should critically evaluate the evidence base of weight loss apps before recommending them.

Specialized training techniques such as forced repetitions/drop sets, supersets, and heavy negatives may enhance muscle hypertrophy.

Practitioners may consider incorporating these specialized techniques into resistance training programs to potentially enhance muscle growth.

Semaglutide is associated with significant weight reductions primarily due to fat mass loss.

Practitioners can expect semaglutide to primarily aid in fat loss for overweight or obese patients.

The proportion of lean mass relative to total body mass increased, suggesting a positive overall outcome.

The increase in lean mass proportion may indicate that semaglutide can help maintain muscle relative to fat loss.

Gamification with support significantly increased mean daily steps by 503 steps compared to the control group over 1 year.

Incorporating gamification with support can effectively enhance physical activity in patients with uncontrolled diabetes.

Gamification with competition significantly increased mean daily steps by 606 steps compared to the control group over 1 year.

Utilizing gamification with competitive elements can effectively boost physical activity in patients with uncontrolled diabetes.

Bariatric/metabolic surgery can improve glucose homeostasis more effectively than any known pharmaceutical or behavioral approach.

Practitioners should consider bariatric surgery as a viable treatment option for improving glucose control in T2D patients.

Endoscopic sleeve gastroplasty (ESG) added 0.06 quality-adjusted life-years (QALYs) and reduced total cost by $33,583 relative to semaglutide.

This indicates that ESG not only provides health benefits but also reduces overall treatment costs.

Effective weight management requires a physician-patient partnership.

Physicians should focus on building supportive relationships with patients to improve weight management outcomes.

Physicians should evaluate a patient's readiness to change and set appropriate weight-loss goals.

Physicians should assess patients' readiness for change and collaboratively set realistic weight-loss goals.

Diet quality changes are associated with long-term weight gain.

Focus on improving diet quality rather than just calorie counting.

Obesity and diabetes require a focus on diet quality and its determinants.

Policy and research should prioritize diet quality over calorie counting.

Diet has become one of the top risk factors for poor health.

Recognize the critical role of diet in health assessments.

Diabetes remission occurred in 57% (46% complete, 11% partial) after Roux-en-Y gastric bypass (RYGB) and 22.5% (16.9% complete, 5.6% partial) after laparoscopic gastric banding (LAGB).

Bariatric surgery, particularly RYGB, can lead to significant diabetes remission in obese patients.

Liraglutide effectively reduces body weight and body fat through mechanisms involving reduced appetite and lowered energy intake.

Liraglutide can be considered as a pharmacotherapy option for weight management in patients with obesity.