Browse the evidence

Lifestyle interventions can reduce the incidence of myocardial infarction and the risk of developing type 2 diabetes.

Encouraging lifestyle changes can significantly lower the risk of serious health issues like heart attacks and diabetes.

The intervention resulted in a significant improvement in fruit and vegetable consumption, increasing by 4% of daily energy intake.

Practitioners can focus on dietary interventions to improve fruit and vegetable intake among nurses.

The Mediterranean diet is advised for cardiovascular prevention in patients with familial hypercholesterolemia (FH).

Practitioners should consider recommending the Mediterranean diet to patients with FH.

Limiting dietary fat and saturated fatty acids is an advised strategy for managing familial hypercholesterolemia.

Practitioners should advise FH patients to limit dietary fat and saturated fatty acids.

Supplementation of phytosterols and fiber can be helpful in managing familial hypercholesterolemia.

Practitioners may consider recommending phytosterol and fiber supplements to FH patients.

Participants assigned to either the in-person or the remote lifestyle intervention were twice as likely as those assigned to the control group to have lost 5% or more of their initial body weight at 2 years.

Incorporating in-person or remote lifestyle interventions can significantly enhance weight loss outcomes in obese patients.

Weight loss at 2 years was similar in the groups that received in-person support (5.1 kg) and remote support (4.5 kg) and was significantly greater than the weight loss in the control group (0.8 kg).

Both in-person and remote support can lead to significant weight loss compared to standard care.

Patients with obesity experienced a median weight change of -5% at 6 months and -4% at 18 months after the intervention.

Practitioners can expect significant weight loss in patients with obesity following a multicomponent lifestyle intervention.

Patients reported increased participation in physical activities by +1 day/week after the intervention.

Encouraging physical activity is essential in lifestyle interventions for obesity.

Nutritional counseling and remote monitoring led to a statistically significant reduction in the average consumption of products containing fats and salt among overweight and obese women.

Practitioners can implement nutritional counseling and remote monitoring to effectively reduce fat and salt intake in overweight and obese patients.

Weight loss interventions can improve reproductive outcomes in women.

Implementing weight loss strategies may enhance fertility treatment success.

Treat weight-loss maintenance differently from weight loss.

Practitioners should emphasize different strategies for maintaining weight loss compared to initial weight loss efforts.

Low-fat diets are best for preventing weight regain.

Practitioners should recommend low-fat diets to clients aiming to maintain weight loss.

Substitution of LCSBs for sugar-sweetened beverages (SSBs) is associated with a reduction in body weight by −0.47 kg and risk of diabetes (RR, 0.94).

Replacing SSBs with LCSBs may aid in weight loss and reduce diabetes risk.

Substitution of LCSBs for SSBs is associated with reduced cardiovascular mortality (RR, 0.95) and total mortality (RR, 0.96).

Switching from SSBs to LCSBs may contribute to lower cardiovascular and total mortality.

Both Colorado and Alabama participants lost significant amounts of weight after a 16-week intervention (CO 13.2 ± 4.9 kg, AL 12.5 ± 5.6 kg) with no significant difference between the states (P = 0.9315).

Weight loss interventions can be effective in different regions without significant differences in outcomes.

A randomized behavioral intervention with recommendations to consume a high fiber diet was conducted.

Practitioners may consider implementing high fiber dietary recommendations in behavioral interventions for gestational weight management.

Sugar-sweetened beverage consumption is independently associated with noncommunicable diseases.

Reducing sugar-sweetened beverage consumption may help mitigate the risk of noncommunicable diseases.

Patients on dialysis achieved a mean total body weight loss of 7.8% (SD 6.1) after being prescribed semaglutide.

Semaglutide may be an effective weight loss intervention for patients on dialysis.

Phase 2 trials of retatrutide report unprecedented weight reductions comparable to bariatric surgery.

Retatrutide may provide an effective alternative to surgical weight loss methods.

Weight loss was consistently larger in the incretin intervention groups than in placebo or lifestyle intervention comparators.

Incretin therapies may be more effective for weight loss compared to lifestyle changes or placebo.

Weight loss significantly explained heterogeneity in treatment effects on fibrosis improvement and MASH resolution.

Weight management should be emphasized in treatment plans for MASH to enhance treatment efficacy.

GLP-1 receptor agonist treatment is associated with a 10.3% reduction in fat mass (FM) at 6 months, 17.3% at 12 months, and 18.0% at 24 months.

GLP-1RA treatment leads to significant fat mass reduction over 24 months.

The study suggests that the combination of CC and WS may enhance weight loss in patients on a mildly hypocaloric diet.

This combination may be recommended as a supplement to support weight loss efforts in conjunction with dietary changes.