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The intervention group achieved a mean body weight change of −9.5% (±4.1) with 90% of participants losing ≥ 5%.

Practitioners can consider remote interventions as effective for weight loss in older adults.

Weight loss reduces the recurrence of symptomatic atrial fibrillation.

Weight management should be a focus in the treatment plan for patients with AF.

Oral semaglutide, 50 mg, led to a mean percentage change in body weight of -14.3% compared to -1.3% with placebo.

Oral semaglutide is effective for significant weight loss in this population.

84.3% of participants on semaglutide achieved a 5% or greater body weight reduction compared to 17.2% on placebo.

A high proportion of patients on semaglutide can expect significant weight loss.

R-ESG offered higher total body weight loss (TBWL%) than GLP1/GIP-RA at 3 months (11.2% vs. 4.3%, p < .001), 6 months (13.5% vs. 6.8%, p < .001), and 12 months (13.4% vs. 9.2%, p = .07).

Practitioners may consider R-ESG as a more effective option for weight loss in patients experiencing weight recidivism after sleeve gastrectomy.

GLP1/GIP-RA achieved significantly lower TBWL% in patients with prior SG compared to those with intact stomach at 3 months (4.3% vs. 5.7%, p = .02), 6 months (6.8% vs. 9.2%, p = .02), and 12 months (9.2% vs. 12.7%, p = .03).

Practitioners should be aware that GLP1/GIP-RA may be less effective for weight loss in patients with prior sleeve gastrectomy compared to those with intact stomachs.

Pharmacists can effectively evaluate and monitor the use of GLP-1 therapy in weight management patients.

Utilizing pharmacists in weight management can enhance patient care and therapy outcomes.

Patients receiving email-based health coaching and Semaglutide therapy lost a mean weight of 9.52% over 5 months.

Email-based coaching combined with Semaglutide can be effective for weight loss in overweight and obese patients.

81.51% of the cohort lost a 'meaningful' amount of weight (5% or more).

A high percentage of participants achieved significant weight loss, indicating the program's effectiveness.

The 'food labels & real-time feedback' and 'ordering' strategies had significantly positive main effects on overall diet quality of the shopping basket.

Implementing food labels with real-time feedback and ordering by nutritional quality can significantly enhance diet quality in online grocery shopping.

Combining 'food labels & real-time feedback' and 'ordering' interventions is more effective than using either intervention alone.

Using a combination of food labels with real-time feedback and ordering can significantly enhance diet quality in online grocery shopping.

A healthy lifestyle is essential for the long-term success of any therapeutic intervention for obesity.

Encouraging lifestyle changes is vital for effective obesity treatment.

Physical activity should be promoted as a foundational component of care for patients receiving NuSH-based treatments for obesity.

Encourage physical activity as part of a comprehensive treatment plan for obesity.

Roux-en-Y gastric bypass (RYGB) surgery is the most effective intervention for weight loss.

RYGB should be considered for patients seeking significant weight loss.

Patients with type 2 diabetes mellitus (T2DM) who followed a 3-month partial meal replacement plan achieved an average weight loss of 7.1±7.0kg at 12 months and 4.2±7.7kg at 24 months.

Implementing a partial meal replacement plan may aid in weight loss for patients with T2DM.

The three isocaloric eating patterns, differing in carbohydrate cellularity and amount, decreased visceral fat volume significantly and to a similar clinically relevant degree.

Practitioners can consider various isocaloric diets for reducing visceral fat in obese patients.

Waist circumference was reduced to a significantly greater degree in the LCHF vs. acellular group at 6 months.

LCHF diets may be more effective for reducing waist circumference compared to acellular carbohydrate diets.

Energy intake of the slow-ER/low-ED meal was 573 kcal (50%) lower compared to the fast-ER/high-ED meal.

Practitioners should consider the impact of meal energy density and eating rate on energy intake when designing meal plans.

A slow-ER and low-ED reduced energy intake by 59% compared to the control meal.

Incorporating slower eating rates and lower energy density foods can significantly reduce caloric intake.

A fast-ER/high-ED increased energy intake by 19% compared to the control meal.

Fast eating rates and higher energy density foods can lead to increased caloric intake, which should be considered in dietary recommendations.

Metabolic surgery results in substantial and sustained weight loss, improvements in comorbidities such as type 2 diabetes, and reduced mortality, and it is cost-effective.

Practitioners should consider metabolic surgery for patients with severe obesity and related comorbidities.

Semaglutide reduces percentage body weight by a mean difference of -10.73 (95% CI -12.24 to -9.21) at medium-term follow-up.

Semaglutide can be an effective treatment option for weight loss in adults with obesity.

Semaglutide increases the proportion of people achieving 5% weight loss with a risk ratio of 2.68 (95% CI 2.30 to 3.12) at medium-term follow-up.

Semaglutide may significantly help adults with obesity achieve clinically relevant weight loss.

Discontinuation of GLP-1 receptor agonists can lead to rapid weight regain and loss of cardiometabolic benefits.

Maintaining adherence to GLP-1 RA therapy is crucial for sustained weight loss and health benefits.