Browse the evidence

Higher intake of white rice (≥450g/d compared with <150g/d) is associated with an increased risk of diabetes (HR: 1.20; 95% CI: 1.03-1.41, p for trend=0.003).

Practitioners should consider advising moderation in white rice consumption to mitigate diabetes risk.

The highest risk of diabetes associated with white rice intake was observed in South Asia (HR: 1.65; 95% CI: 1.17-2.34, p for trend=0.02).

Healthcare providers in South Asia should be particularly aware of the diabetes risk linked to high white rice consumption.

Overfeeding reduced insulin sensitivity more in individuals with short sleep duration compared to those with longer sleep duration.

Encouraging adequate sleep may mitigate negative effects on insulin sensitivity during overeating.

Retatrutide shows additional benefits for metabolic comorbidities such as NASH and cardiovascular disease.

Retatrutide may help manage obesity-related metabolic conditions.

Higher percentage body fat (PBF) is associated with successful weight reduction in both male (OR = 3.990) and female (OR = 2.266) patients.

Monitoring body fat percentage may help predict weight loss success in patients undergoing GLP-1RA treatment.

Surgical treatment of obesity is more effective in treating obesity-associated diseases than conservative treatment.

Surgical options may be prioritized for patients with obesity-related health issues.

Weight re-gain is a common concern after bariatric procedures.

Clinicians should prepare patients for the possibility of weight re-gain and consider revisional surgery options.

Exenatide combined with Metformin improved 2-hour oral glucose tolerance test (OGTT) values by a mean difference of -1.78 (p < 0.001).

The combination therapy may enhance glucose tolerance in women with PCOS.

The article discusses weight loss dependent and weight loss independent mechanisms for improvement in cardiometabolic health.

Practitioners should consider both weight loss dependent and independent factors when assessing cardiometabolic improvements.

MRs significantly reduce glycated hemoglobin (HbA1c) levels by 0.24%.

Using meal replacements can lead to better long-term glucose management.

MRs cause a greater decrease in FBS, insulin, and HOMA-IR in individuals over 50 years old compared to those aged 50 years or younger.

Older adults may benefit more from meal replacements in terms of glucose metabolism.

The GTSS group had significantly lower postprandial glucose excursion compared to the standardized breakfast group.

GTSS may provide a more stable postprandial glucose response compared to standard breakfasts.

There is evidence for the association between intake of high-quality carbohydrates and body weight.

Practitioners should encourage the consumption of high-quality carbohydrates for weight management.

Chronic nutritional carbohydrate overload has disruptive metabolic effects and detrimental health consequences.

Reducing carbohydrate intake may improve metabolic health.

Intermittent fasting, caloric restriction, exercise, and ketogenic diet have positive metabolic effects through modulation of redox homeostasis.

Incorporating these practices may enhance metabolic health.

Progressing up to maximum recoverable volume (MRV) may be unnecessary and suboptimal for hypertrophy.

Avoid pushing training volume to the maximum recoverable level to optimize hypertrophy outcomes.

Both training programs resulted in significant reductions in LDL cholesterol, with linear training showing a decrease of -15.1 mg·dL-1 and undulating-periodized training showing a decrease of -9.4 mg·dL-1.

Implementing these training programs can help lower LDL cholesterol in older adults.

Highly trained endurance cyclists can perform intense interval training sessions during short-term exposure to a high-fat diet despite their increased subjective ratings of effort.

Coaches can consider incorporating high-fat diets for trained athletes without compromising performance.

The rate of fat oxidation increased from 31 ± 13 μmol.kg−1.min−1 on d-2 to 61 ± 25 μmol.kg−1.min−1 on d-5 after FAT-ADAPT.

Athletes may enhance fat oxidation through short-term high-fat dietary adaptations.

Blood [lactate] after FAT-ADAPT declined from 3.7 ± 1.2 mM on d-2 to 2.4 ± 0.5 mM on d-5.

A high-fat diet may lead to lower lactate accumulation during intense exercise.

Both healthy low fat (HLF) and healthy low carbohydrate (HLC) diets improved indices of insulin sensitivity after 12 months.

Both diets can be recommended for improving insulin sensitivity in overweight adults.

Ingestion of a high-fat meal increased subsequent fat availability and utilization during intense exercise compared to carbohydrate feedings.

Practitioners may consider high-fat meals to enhance fat utilization during intense exercise.

Fat feeding elevated plasma free fatty acids (FFA) and lowered respiratory exchange ratio (RER) during steady-state exercise.

High-fat meals may enhance fat metabolism during exercise.

Higher intake of white rice (≥450g/d compared with <150g/d) is associated with an increased risk of diabetes (HR: 1.20; 95% CI: 1.03-1.41, p for trend=0.003).

Practitioners should consider the potential diabetes risk associated with high white rice consumption in dietary recommendations.