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Myofibrillar protein synthesis is positively correlated with blood pH.

Practitioners may need to consider blood pH levels when assessing muscle protein synthesis.

The online exercise program had good feasibility and adherence, with 97% attendance and 98% participant satisfaction.

Practitioners can consider online exercise programs as a feasible option for engaging older adults.

The intervention showed a significant reduction in depression scores in the ACTIVE group compared to the CON group.

Implementing online exercise programs may help reduce depression in older adults.

Obesity negatively impacts ovarian stimulation and is associated with reproductive disorders.

Addressing obesity may improve fertility treatment outcomes.

The COSIAM method provides a viable approach for assessing muscle protein turnover in young, healthy females.

Practitioners can use the COSIAM method for accurate assessment of muscle protein turnover in young females.

An increase of 1 serving/day of low calorie sweetened beverages (LCSBs) is associated with reduced body weight by −0.07 kg and waist circumference by −1.35 cm.

Increasing LCSB intake may help in weight management for individuals at risk for or with diabetes.

People with physical disabilities (PWD) report more sedentary time compared to people without disabilities (PWoD) (β = 0.34; 95 % CI = 0.16-0.52, p < 0.001).

Practitioners should be aware that PWD may require tailored interventions to reduce sedentary behavior.

PWD have greater odds of reporting zero total physical activity compared to PWoD (OR = 5.18, 95 % CI = 2.19-12.24, p < 0.001).

Interventions for PWD should focus on increasing overall physical activity levels.

Alabama participants showed significantly greater improvements in objective physical activity measures compared to Colorado participants.

Regional differences may influence physical activity outcomes in weight loss interventions.

The effects of resistance training at longer muscle lengths show an increasing trend from proximal to distal sites.

Practitioners may consider the trend when designing resistance training programs, but should note the trivial nature of the differences.

There was stronger support for general inter-individual response variation (GEN) compared to condition-specific response variation (CON).

Understanding general response variation can help tailor training programs more effectively.

Gross variability in resistance training outcomes often reflects confounding sources of within-participant variation rather than true inter-individual differences.

Practitioners should be cautious in interpreting variability in training outcomes.

The Brain and Body Health (BB-Health) study aims to demonstrate the feasibility of a multicomponent nutritional supplement (MCNS) and weight loss (WL) intervention for older adults with obesity.

Practitioners may consider the potential of MCNS and WL interventions for older adults with obesity.

If the BB-Health protocol demonstrates feasibility, the MCNS with and without WL intervention has potential to prevent age-related cognitive decline.

Practitioners may consider the implications of MCNS and WL interventions for cognitive health in older adults.

Ghrelin concentration significantly reduces post-meal in both moderate and high protein diets.

Both moderate and high protein diets effectively reduce ghrelin levels, indicating a potential for managing hunger.

Perceived hunger, fullness, and satisfaction were comparable between the moderate and high protein diets.

Practitioners can expect similar levels of hunger and satisfaction from both moderate and high protein diets.

Including simple variables such as body mass and sex in regression models improved the predictions of accelerometer-assessed TEE.

Incorporating individual characteristics like body mass and sex can enhance the accuracy of TEE assessments using accelerometers.

Higher intake of white rice (≥450g/d compared with <150g/d) is associated with an increased risk of diabetes (HR: 1.20; 95% CI: 1.03-1.41, p for trend=0.003).

Practitioners should consider advising moderation in white rice consumption to mitigate diabetes risk.

The highest risk of diabetes associated with white rice intake was observed in South Asia (HR: 1.65; 95% CI: 1.17-2.34, p for trend=0.02).

Healthcare providers in South Asia should be particularly aware of the diabetes risk linked to high white rice consumption.

Overfeeding led to an average body weight gain of 7.3 ± 0.4 kg.

Practitioners should be aware that overfeeding can lead to significant weight gain.

Overfeeding reduced insulin sensitivity more in individuals with short sleep duration compared to those with longer sleep duration.

Encouraging adequate sleep may mitigate negative effects on insulin sensitivity during overeating.

GLP-1 receptor agonists have shown promising results in reducing liver enzymes and improving MASLD.

Practitioners may consider GLP-1 RAs as a therapeutic option for MASLD.

The long-acting GIPR agonist LY3537021 induced a mean body weight loss of 3.14 kg in participants with T2D compared to 0.36 kg in the placebo group at day 57 (p < 0.05).

LY3537021 may be an effective treatment option for weight loss in patients with T2D.

LY3537021 was well tolerated with infrequent gastrointestinal adverse events.

LY3537021 may be a safe option for patients with T2D.