Browse the evidence

INV-202 produced a significant mean weight loss of 3.5 kg (3.3% compared with placebo participants who gained a mean 0.6 kg [0.5%]).

INV-202 may be an effective treatment for weight loss in individuals with metabolic syndrome.

INV-202 exhibited significant reductions in waist circumference and BMI (P ≤ 0.03).

INV-202 may help reduce waist circumference and BMI in this population.

Strategies targeting muscle mass and function losses within an ICU setting are essential to improve patient-related outcomes.

Practitioners should implement strategies to maintain muscle mass in ICU patients.

Older ICU patients seldom meet the recommended protein intake.

Increase protein provision for older ICU patients to meet recommendations.

Whey protein supplementation increases lean mass by 0.37 kg without influencing changes in fat mass.

Whey protein can be recommended for women looking to increase lean mass without gaining fat.

The beneficial effect of whey protein on lean mass is more robust when combined with energy restriction.

Combining whey protein with energy restriction may yield better results for increasing lean mass.

Masters athletes may benefit from higher doses of postexercise dietary protein due to slower recovery rates after muscle-damaging exercise.

Practitioners should consider recommending higher protein intake for masters athletes postexercise.

Postexercise protein feeding is important for endurance athletes to create a positive net muscle protein balance.

Endurance athletes should prioritize postexercise protein intake for recovery.

Group interventions were favoured over one‐to‐one interventions for weight loss at 12 months (−1.9 kg).

Practitioners may consider group interventions as more effective for weight loss in overweight adults.

Participants of group interventions were more likely to attain ≥5% weight loss at 12 months relative to one‐to‐one interventions (relative risk = 1.58).

Group interventions may enhance the chances of participants achieving significant weight loss.

Group multi‐component lifestyle interventions are superior for weight loss compared to one‐to‐one interventions.

For effective weight management, group interventions should be prioritized over one-to-one formats.

Body fat was reduced from 20.3% to 12.2% before the first competition and declined to 11.6% before the second competition.

Practitioners can expect significant fat loss in experienced competitors during contest preparation.

Fat-free mass increased by 2.1% before the first competition and peaked at 4.6% above baseline in the recovery period.

Practitioners should note that muscle gain can occur during recovery after competition.

Technology-assisted behavioral interventions may be effective for producing weight loss among overweight and obese adults.

Healthcare professionals can consider using technology-assisted interventions to support weight loss in patients.

An active perioperative GLP-1 RA prescription in patients with diabetes was associated with a significantly reduced risk of 30-day readmission (RR: 0.883; P = 0.028).

Practitioners may consider GLP-1 RA prescriptions to reduce readmission rates in diabetic surgical patients.

Persons consuming fatty fish twice per week had a 47% lower risk of coronary death compared with those who consumed fatty fish less than once per month.

Encouraging the consumption of fatty fish may reduce coronary death risk in older adults.

Cardiac rehabilitation programs should develop behavioral weight loss programs to assist cardiac patients in losing weight and improving risk factors.

Practitioners should consider integrating behavioral weight loss strategies into cardiac rehabilitation programs.

A comprehensive, behavioral-based approach is the most effective treatment strategy for obesity in cardiac patients.

Practitioners should implement comprehensive behavioral strategies to address obesity in cardiac patients.

The MR group experienced a significantly higher increase in lean mass, strength, and power than the PR group after 6 weeks of resistance training.

Incorporating high-protein dairy milk post-exercise and pre-sleep may enhance muscle gains and strength in young males undergoing resistance training.

Serum levels of IGF-1, growth hormone, testosterone, and follistatin increased, while cortisol and myostatin decreased in the MR group compared to the PR group.

Monitoring hormonal responses may provide insights into the effectiveness of dietary interventions in resistance training.

Strategic ingestion of high-protein dairy milk augmented lean mass, strength, power, and altered serum concentrations of skeletal muscle regulatory markers.

Implementing high-protein dairy milk in post-exercise and pre-sleep nutrition can enhance training outcomes.

Cessation of regular exercise will likely be associated with a high risk of positive fat balance and weight gain.

For practitioners, this highlights the importance of maintaining regular exercise to prevent weight gain.

Individualized FATmax training reduced body fat% in older women with type 2 diabetes (p<0.001).

Practitioners can consider FATmax training as an effective method for reducing body fat in older women with type 2 diabetes.

Individualized FATmax training improved insulin resistance in older women with type 2 diabetes (p<0.001).

FATmax training may be recommended to improve insulin sensitivity in this population.