Browse the evidence

Collagen supplementation did not change integrated MPS rates compared to the RDA.

Collagen may not be effective for enhancing muscle protein synthesis in older males.

Semaglutide showed a favorable hepatic safety profile with no discontinuations due to liver enzyme elevations.

Semaglutide can be considered safe for liver health in the studied population.

Higher in vivo adipose cell turnover is positively associated with BMI and VAT/TAT.

Practitioners should consider the role of adipose cell turnover in assessing metabolic health in obese individuals.

Preadipocyte and adipocyte formation is negatively associated with insulin sensitivity.

This finding suggests that higher adipocyte formation may be detrimental to insulin sensitivity, which is crucial for metabolic health.

A single-site measure of muscle shape does not adequately capture the effects of exercise training interventions.

Multiple measurement sites should be used to assess training effects accurately.

There is no significant difference in muscle hypertrophy between segments in the placebo group.

Placebo may not be effective for muscle hypertrophy in resistance training contexts.

Egg yolk intake does not further enhance muscle mass compared to egg whites in high-protein diets.

For those on high-protein diets, egg yolks may not provide additional muscle mass benefits over egg whites.

Obstructive sleep apnea is a common comorbidity in individuals with obesity.

Healthcare providers should be aware of the high prevalence of obstructive sleep apnea in obese patients.

There were no differences in antioxidant capacity markers and protein oxidation adducts between the traditional and pyramid training groups.

Both training systems are equally effective in improving oxidative stress markers.

C-reactive protein levels decreased after one year of GLP1-RA treatment.

Monitoring C-reactive protein levels may help assess the effectiveness of GLP1-RA in IBD.

Obesity and its associated conditions significantly impact healthcare systems, life expectancy, and quality of life.

Addressing obesity is crucial for improving healthcare outcomes and quality of life.

High-dose leucine supplementation did not enhance gains in muscle strength after a 12-week resistance training program.

Practitioners should consider that leucine supplementation may not provide additional benefits for muscle strength in adequately protein-fed individuals.

There were no differences in muscle cross-sectional area (mCSA) gains between the leucine and alanine groups.

Leucine supplementation does not provide additional benefits for muscle size compared to alanine in resistance-trained individuals.

Pea protein supplementation had an intermediate, non-significant effect on muscle damage biomarkers compared to water.

Pea protein may offer some benefits for muscle recovery, but less effectively than whey protein.

New pharmacological treatments for obstructive sleep apnea (OSA) might be effective.

Practitioners should consider new pharmacological options for treating OSA.

Ten proteins were associated with different rates of weight regain, some specifying pathways of chemotaxis and innate immune responses.

Identifying specific proteins may help tailor interventions for weight regain.

Gut-derived signals significantly modulate outcomes after bariatric surgery.

Understanding gut-derived signals can help in developing interventions for obesity.

High responders to hypertrophic strength training showed a decrease of -10.5% in vastus lateralis cross-sectional area (VLCSA) during detraining.

Practitioners should be aware that high responders may experience significant muscle loss during periods of detraining.

Common cardiovascular conditions, such as heart failure with preserved ejection fraction, can be conceptualized as a consequence of accelerated aging.

Understanding the link between aging and heart failure can guide prevention and management strategies.

Genetic predisposition to higher waist-to-hip ratio adjusted for BMI (WHRadjBMI) predicts an increase in waist circumference after weight loss.

Practitioners should consider genetic predisposition when assessing potential waist circumference changes after weight loss.

Remission of diabetes may not be permanent and can result in glycemic relapse over time.

Clinicians should communicate the potential for relapse when discussing remission with patients.

Relevant articles on cardiovascular disease prevention in obesity, atherogenic dyslipidaemia, and chronic kidney disease have been included.

Practitioners should consider the impact of obesity and related conditions on cardiovascular health.

Rapid weight loss induced by semaglutide can lead to noticeable facial volume loss and the appearance of a prematurely aged face, referred to as 'Ozempic face.'

Healthcare providers should be aware of the potential cosmetic implications of semaglutide use for weight loss.

The characteristics of 'Ozempic face' occur in people much younger than what is seen with the natural aging process.

Clinicians should consider age-related factors when assessing patients for semaglutide treatment.