Browse the evidence

Caffeine and coffee have varied physiological effects.

Practitioners should consider the diverse effects of caffeine and coffee on health.

Caffeine and coffee are associated with risks of cardiovascular disease, insulin resistance, gallstones, cancer, and liver disease.

Health professionals should be aware of the potential risks associated with caffeine and coffee consumption.

Seven French raw-milk cheeses showed biological activities in vivo and in vitro.

Cheeses may be considered functional foods with potential health benefits.

Fractions (polar and apolar) reduced inflammatory markers in human chondrocytes.

Cheese fractions may have potential anti-inflammatory effects on joint health.

The association between MVD and incident HF remains significant after adjusting for the development of coronary artery disease.

Consideration of MVD is crucial in assessing heart failure risk in diabetic patients.

The hazard ratios for heart failure by type of microvascular disease are 2.22 for nephropathy, 1.30 for retinopathy, and 1.33 for neuropathy.

Different types of MVD should be evaluated for their specific risks in heart failure.

Participation in abdominal crunches may increase the risk for low back pain.

Practitioners should weigh the benefits against the potential risk of low back pain when recommending this exercise.

GLP-1-based therapies can lead to significant aesthetic issues in the face and neck, including midface volume loss and increased skin laxity.

Practitioners should be aware of these aesthetic concerns when treating patients on GLP-1 therapies.

Multimodal nonsurgical aesthetic treatments are recommended for addressing aesthetic issues in GLP-1 weight loss patients.

Practitioners should consider a combination of treatments for optimal aesthetic outcomes.

MitoQ supplementation reduced mitochondrial H2O2 emission capacity in skeletal muscle.

MitoQ may reduce oxidative stress in skeletal muscle for older adults.

Individuals with type 2 diabetes have significantly higher levels of inflammatory markers compared to an unaffected population.

Practitioners should consider monitoring inflammatory markers in patients with type 2 diabetes.

There is a significant positive association between C-reactive protein (CRP) levels and body mass index (BMI) in individuals with type 2 diabetes.

Monitoring BMI may provide insights into inflammation levels in diabetic patients.

The study reported no substantial differences in the numbers of adverse events between the two groups.

Both dietary approaches appear to be safe with respect to adverse events.

GLP‐1RAs triggered more gastrointestinal adverse events than placebo, with no in‐between difference.

Clinicians should be aware of the gastrointestinal side effects associated with GLP-1RAs when prescribing these medications.

Women with birth weights < 5.0 lb have an age-adjusted odds ratio of 1.39 for hypertension compared to those in the middle category of birth weight in NHS I.

Practitioners should consider birth weight as a potential risk factor for hypertension in women.

The proportion of free fatty acid molecules undergoing primary reesterification doubled over the physiological portion of the insulin dose-response curve.

Increased insulin levels significantly enhance the reesterification of free fatty acids, which may impact metabolic health.

Akt Thr(308) phosphorylation was unaltered after either bout of exercise.

Neither endurance nor resistance exercise affects Akt Thr(308) phosphorylation in trained individuals.

There is a need for intensified collaboration between the disciplines of nutrition and pharmacology.

Collaboration between nutritionists and pharmacologists can lead to improved health outcomes.

The proportion of free fatty acid molecules undergoing primary reesterification doubled over the physiological portion of the insulin dose-response curve.

Increased insulin levels can significantly enhance the reesterification of fatty acids, which may impact fat storage and metabolism.

No significant changes occurred in bone density or bone geometry at any site.

BWSTT does not improve bone density in this population.

Whole-body bone density exhibited a small but statistically significant decrease (p < 0.006).

Practitioners should be aware that BWSTT may not prevent bone density loss.

Percentage body fat (PFAT) is a highly familial trait with a heritability estimate of 0.76.

Practitioners should consider PFAT as a significant genetic factor in assessing diabetes risk.

Human adenovirus Ad-36 induces commitment, differentiation, and lipid accumulation in human adipose-derived stem cells (hASC).

Practitioners should consider the role of Ad-36 in adipogenesis when addressing obesity.

Ad-36 significantly increases hASC differentiation even in the absence of adipogenic inducers.

Ad-36 may be a factor in adipocyte differentiation in clinical settings.