Browse the evidence

Tirzepatide induces significant weight loss: 7.5 kg (5 mg/week), 11 kg (10 mg/week), and 12 kg (15 mg/week) compared to placebo.

TZP can be considered for weight management in patients with T2D and obesity.

Endoscopic sleeve gastroplasty (ESG) is safe and effective in patients with a BMI of 27-30, with a mean total weight loss of 11.0% at 6 months and 15.5% at 12 months.

Practitioners can consider ESG as a viable option for overweight patients seeking weight loss.

With the inclusion of dietary supplements, percentages below the EAR for all nutrients (except protein) were lower than those for food alone.

Incorporating dietary supplements may help mitigate nutrient deficiencies in calorie-restricted diets.

More participants became pregnant in the low-volume HIT (LV-HIT) group than in the control group.

This indicates that low-volume HIT may have a positive effect on fertility in women with PCOS.

Preoperative weight loss significantly improves long-term weight loss outcomes.

Encouraging preoperative weight loss may enhance surgical outcomes for patients.

AOM-naïve patients experienced superior weight loss outcomes with semaglutide compared to non-AOM-naïve patients at 3, 6, 9, and 12 months.

Practitioners should consider that patients who have not previously used anti-obesity medications may achieve better weight loss results with semaglutide.

Nutrition periodization is crucial for optimal performance and body composition in football players.

Coaches and nutritionists should tailor diets to training phases for better performance.

Carbohydrates are emphasized for glycogen replenishment and recovery during the competitive period.

Focus on carbohydrate intake during competitive phases for optimal recovery.

Resistance training increased fat-free mass (FFM) and strength gains similarly in the three groups.

Resistance training is effective for increasing muscle mass and strength regardless of protein supplementation.

Fat-free mass (FFM) increased by 2.3% in the whey protein group, 3.6% in the chia flour group, and 3.0% in the placebo group.

The study provides specific data on how much FFM increased in each group, which can inform future research and practice.

UPFs increase the risk of chronic diseases and death.

Public health initiatives should address the risks associated with UPF consumption.

A 3-month regimen of nutrition counseling and high-intensity resistance training resulted in a 6.6% reduction in body fat and a 1.4% increase in muscle mass.

Practitioners can implement similar exercise and nutrition regimens to promote fat loss and muscle gain in breast cancer patients.

All groups demonstrated improvements in the measured outcomes.

Resistance training is effective for improving strength and muscle outcomes in females.

A 20-min walk post-breakfast reduces postprandial hyperglycaemia in Early (0700 h) and Delayed (1200 h) conditions.

Encouraging a short walk after breakfast may help manage blood sugar levels in patients with type 2 diabetes.

A 12-week partial meal replacement (PMR) diet is effective for weight loss in overweight or obese patients after ischemic stroke, with 52.9% of participants achieving ≥5% weight loss compared to 11.9% in the standard care group.

Healthcare providers can consider PMR diets as a viable option for weight management in stroke patients.

Behavioral treatment for obesity includes components such as self-monitoring, functional analyses, stimulus control, cognitive restructuring, problem-solving, and relapse prevention.

Practitioners should incorporate these components into obesity treatment programs.

Weight loss requires the induction of a negative energy balance.

Weight loss strategies should focus on creating a negative energy balance.

Patient-delivered lifestyle intervention yielded significantly less weight regain than standard-of-care (SOC) at month 18 (0.77 kg vs 2.37 kg; P = .002).

Patient-delivered interventions may be a viable alternative for weight loss maintenance.

Patient-delivered intervention showed parallel improvements in diastolic blood pressure, heart rate, physical activity, and sedentary behavior compared to SOC.

Improving cardiovascular metrics can enhance overall health in weight maintenance programs.

During peak week, frequency, volume, and intensity of resistance training decreased while repetition ranges of compound exercises increased.

Competitors should focus on adjusting their training load to reduce stress while increasing repetitions for compound movements.

Each 100 MET-min/wk increase in accelerometry-measured moderate-to-vigorous physical activity (MVPA) from baseline to 4 years is associated with decreased risk of cardiovascular disease (CVD) outcomes.

Encouraging long-term engagement in MVPA can help reduce CVD risk in this population.

Increased accelerometry-measured MVPA from baseline to year 4 is associated with decreased risk of CVD outcomes.

Long-term engagement in MVPA is crucial for reducing CVD risk in this demographic.

Semaglutide led to a mean relative weight loss of 13.3 ± 11.3% after 12 months in adults with type 1 diabetes.

Practitioners can consider semaglutide as an effective option for weight management in overweight/obese patients with type 1 diabetes.

Initiation of semaglutide was significantly associated with a -3.8% reduction in weight at 13 to 24 months.

Semaglutide may be an effective option for weight management in adults.