Browse the evidence

>10% weight loss is strongly associated with major macrovascular events (HR, 1.75; 95% CI, 1.26-2.44) in patients with type 2 diabetes.

>10% weight loss in patients with type 2 diabetes should prompt further cardiovascular risk assessment.

Lifestyle modification remains the cornerstone of MASLD/MASH management alongside semaglutide.

Practitioners should emphasize lifestyle changes in addition to pharmacotherapy for optimal management.

High-Intensity Interval Training (HIIT) improves cardiorespiratory fitness and health.

HIIT can be effectively incorporated into fitness training programs to enhance fitness levels.

Lifestyle interventions should be the first line of defense against the development of type 2 diabetes (T2D).

Practitioners should prioritize lifestyle modifications in T2D prevention strategies.

A 3-year healthy eating and physical activity intervention improves several cardiometabolic risk markers in men despite partial body weight regain.

Practitioners can implement long-term lifestyle interventions to improve cardiometabolic health in similar populations.

Power output in the closing sprints of exhaustive time trial cycling increased with creatine ingestion.

Creatine supplementation may enhance performance in the final stages of endurance cycling events.

Ingestion of a sports bar enhanced fat oxidation during prolonged, submaximal exercise compared to carbohydrate ingestion.

Using a sports bar may improve fat utilization during long-duration cycling.

Total fat oxidation was significantly higher when ingesting the sports bar compared to carbohydrate.

Higher total fat oxidation may benefit endurance performance.

Tai Chi exercise therapy significantly decreases fasting blood glucose (FBG) by an average of 0.79 mmol/L in patients with type 2 diabetes mellitus (T2DM).

Incorporating Tai Chi into exercise prescriptions may help lower blood glucose levels in T2DM patients.

Tai Chi exercise therapy significantly decreases glycated hemoglobin (HbA1c) by an average of 1.10% in patients with T2DM.

Tai Chi may be an effective intervention for improving long-term glucose control in T2DM patients.

In females, egg consumption >50 g/d is associated with a 34% lower risk of central obesity.

Encouraging egg consumption in females may help reduce the risk of central obesity.

Personalized nutrition informed by genetic and metabolic profiling is a promising approach to tailor recovery strategies.

Tailoring recovery nutrition based on individual profiles can enhance recovery outcomes.

Exercise is a key component of nonalcoholic fatty liver disease (NAFLD) treatment.

Practitioners should incorporate exercise into treatment plans for NAFLD.

The effectiveness of exercise in improving NAFLD is influenced by exercise type, intensity, and volume.

Exercise programs should consider these factors to optimize treatment outcomes.

Regular physical activity participation can aid in preventing chronic diseases.

Encouraging regular physical activity is essential for chronic disease prevention.

Tirzepatide exhibited favorable effects on glycemic control, with reductions in HbA1c levels ranging from 20.4 mmol/mol with the 5 mg dose to 28.2 mmol/mol with the 15 mg dose.

Tirzepatide may improve glycemic control in patients with T2DM.

Tirzepatide resulted in mean waist circumference reductions ranging from 4.3 to 9.8 cm across subgroups.

Tirzepatide is effective in reducing waist circumference in East Asian individuals with type 2 diabetes.

Aerobic capacity increased only after HIIT and ENT by +14% ± 7% and +11% ± 11% respectively (P < 0.05).

HIIT and endurance training are effective for improving aerobic capacity in middle-aged men.

Retatrutide and orforglipron are effective in weight loss and improving metabolic parameters associated with obesity.

These drugs may be considered as therapeutic options for obesity management.

Specific dietary compositions may work better for identifiable groups of overweight/obese individuals based on their individual metabolic status.

Dietary prescriptions may need to be tailored based on individual metabolic characteristics.

Specific dietary compositions may work better for identifiable groups of overweight/obese individuals based on their individual metabolic status.

Practitioners may consider individual metabolic status when prescribing dietary plans.

Weight reduction and management strategies may improve chronic kidney disease outcomes.

Weight management should be considered as part of CKD treatment plans.

Nutritional strategies are necessary to confront adaptations to body mass loss.

Dietitians should implement specific nutritional strategies to support weight loss efforts.

A moderate-fat (MFAT) diet lowers triglycerides and improves the total cholesterol:HDL cholesterol ratio.

A moderate-fat diet may be more beneficial for maintaining healthy lipid levels in athletes.