Browse the evidence

Physical activity may prevent certain cancers, including colon and breast cancer.

Encouraging physical activity may help in cancer prevention strategies.

Physical activity is important for regulating body weight, but many cardiometabolic benefits of exercise are independent of such regulation.

Physical activity should be promoted for its broad health benefits, not just weight management.

Obesity and insulin resistance are associated with compromised muscle proteostasis.

Understanding the impact of obesity on muscle health can guide interventions.

HIIT tends to benefit proteostasis by increasing muscle protein turnover rates.

HIIT may be a beneficial strategy for enhancing muscle health in obese individuals.

WG patients were more likely to report sustaining 12 of 12 wellness behaviors than patients who received TC.

Practitioners may consider group settings to enhance patient adherence to wellness behaviors.

The vasti, soleus, and gluteus maximus generated the largest upward accelerations of the center of mass during the barbell back squat.

Strength coaches should focus on training the vasti, soleus, and gluteus maximus for improved squat performance.

Muscle function during squatting is task and posture specific, depending on joint position and environmental interaction.

Practitioners should consider joint positions and task-specific demands when designing squat training programs.

The Ab Wheel Rollout exercise emphasizes the muscle action of the Pectoralis Major and Rectus Abdominis more than the Latissimus Dorsi and Erector Spinae.

Practitioners should focus on the Pectoralis Major and Rectus Abdominis when incorporating the Ab Wheel Rollout into training programs.

There were significant increases in Rectus Abdominis muscle activity between neutral vs. 90º, neutral vs. 150º and 90º vs. 150º.

Adjusting shoulder angles during the Ab Wheel Rollout can significantly enhance Rectus Abdominis activation.

There was a significant increase in Pectoralis Major muscle activity between neutral and 150º positions.

Practitioners should note that changing arm angles can enhance Pectoralis Major activation during the exercise.

Dual and triple agonists show effectiveness on validated surrogate NAFLD biomarkers.

There is potential for dual and triple agonists to be effective in treating NAFLD, warranting further investigation.

The dropout rate was higher in the control group (22.5%) compared to the psychological counseling group (0.0%) (p < 0.001).

Practitioners should consider the importance of psychological counseling in reducing dropout rates.

Quality of life improved among adolescents from both groups, but those in the psychological counseling group reported a better quality of life.

Psychological counseling may enhance the overall quality of life in obese adolescents undergoing treatment.

Mean sedentary bout times were significantly associated with higher percent body-fat in women (b=1.09, 95% CI 0.16 to 2.03, p=0.02), but not men.

Practitioners should consider the duration of sedentary bouts when addressing body-fat in women.

The negative association of higher total number of sedentary bouts with percent body-fat approached significance in women (b=−0.07, −0.14 to 0.00, p=0.06), but not men.

Encouraging more breaks in sedentary behavior may benefit women's body-fat levels.

These findings provide preliminary evidence on the potential importance for human health of avoiding prolonged periods of being sedentary, independent of physical activity.

Reducing prolonged sedentary time may enhance overall health.

Exercise results in a stimulation of muscle protein fractional synthetic rate (FSR) at 3 hours post-exercise to 112% greater than resting levels.

Practitioners should note that muscle protein synthesis is significantly elevated shortly after resistance exercise.

Muscle protein FSR remains elevated 48 hours after exercise compared to resting levels.

Practitioners can expect prolonged benefits in muscle protein synthesis following resistance training.

48% of individuals exhibited exercise-related energy compensation (ExEC) with a mean of −308 ± 158 kcals/day.

Practitioners should note that a significant portion of individuals may not fully compensate for exercise energy expenditure.

Exercise-related energy compensation occurs independent of metabolic adaptation.

This indicates that practitioners should not expect metabolic adaptations to accompany energy compensation from exercise.

The mean thoracolumbar muscle endurance (TLME) time for flexors is 163 ± 106 seconds, while for extensors it is 105 ± 57 seconds.

Practitioners should consider these endurance times when assessing muscle performance in women engaged in resistance training.

Flexor to extensor imbalances are more pronounced among resistance training participants compared to general population reference values.

Awareness of these imbalances can help practitioners design balanced training programs.

It is questionable whether combining BFR with traditional aerobic training can preserve or potentiate hypertrophic adaptations.

Practitioners should be cautious when combining BFR with aerobic training, as the effects on hypertrophy are not well established.

GIP receptor agonism and antagonism both lead to weight reduction.

Both GIP receptor agonists and antagonists could be explored for obesity treatment strategies.