Browse the evidence

Creatine supplementation demonstrated non-significant effects on muscle strength (SMD = 0.03, 95% CI: -0.35, 0.42) but yielded the most pronounced improvement in muscle mass (MD = 2.18, 95% CI: 0.92, 3.44).

Creatine may be beneficial for increasing muscle mass in older adults, but its effect on strength is not significant.

The weekend warrior (WW) physical activity pattern is associated with significantly lower odds of sarcopenia compared to regularly active (RA) individuals (OR 0.25; 95% CI, 0.11-0.56).

Promoting weekend high-intensity workouts may be beneficial for older adults to lower sarcopenia risk.

High-protein diets (1.6 or 3.2 g kg−1 d−1) combined with resistance training (RT) or concurrent training (CT) for 16 weeks had no adverse effects on bone tissue parameters in resistance-trained males.

Practitioners can recommend high-protein diets for resistance-trained individuals without concern for negative effects on bone health.

There were significant time effects noted for the BMD of the pelvis and the BMC of the right ribs.

Practitioners should monitor bone health parameters over time in resistance-trained individuals on high-protein diets.

Approximately 1-in-10 participants met the resistance training guidelines.

Only a small fraction of the population adheres to recommended resistance training guidelines.

The increase in body protein mass due to the energy surplus was correlated with an increase in fat mass (r = 0.820, p = 0.002).

Increased body fat may play a role in promoting body protein mass gain.

Type 2 diabetes mellitus doubles the risk of cardiovascular morbidity and mortality.

Healthcare providers should be aware of the increased cardiovascular risks in patients with Type 2 diabetes.

Continuous glucose monitoring (CGM) can help patients better manage their metabolic control during exercise.

Incorporating CGM technology can enhance exercise safety and effectiveness for diabetic patients.

The study will evaluate both quantitative and qualitative effects of the SALUD program.

The dual evaluation approach can provide comprehensive insights for T2DM interventions.

A gradual decrease in total body fat and no decrease in appendicular lean mass (ALM) are significantly independently associated with higher cognitive scores compared with other trajectories.

Weight loss strategies should focus on reducing body fat while preserving lean mass to support cognitive health.

Differences in cognitive score were large for sarcopenia, but not for obesity.

Addressing sarcopenia may be crucial for maintaining cognitive function in this population.

Weight loss approaches that preserve ALM and function may lead to reduced cognitive decline compared with weight loss alone.

Practitioners should consider strategies that maintain lean mass during weight loss to support cognitive health.

The intervention group exhibited improved self-efficacy (Z = 4.06, P < 0.001) compared to the control group.

Enhancing self-efficacy through targeted interventions can support behavior change in physically inactive young adults.

Responders to the PF regimen exhibited enhanced metabolic flexibility compared to non-responders.

Personalized dietary interventions may enhance metabolic flexibility in patients with T2D.

Glucagon-like peptide 1 receptor agonists consistently reduce three-point major adverse cardiovascular events (MACE) in patients with overweight, obesity, and established cardiovascular disease (CVD) with and without diabetes.

Practitioners can consider glucagon-like peptide 1 receptor agonists as effective treatments for reducing cardiovascular events in eligible patients.

Semaglutide and tirzepatide improve symptoms and functional capacity in obesity-related heart failure of preserved ejection fraction and reduce worsening heart failure events.

Practitioners can use semaglutide and tirzepatide to improve heart failure symptoms in patients with obesity.

Metabolic bariatric surgery is associated with durable weight loss and lower observed rates of major adverse cardiovascular events (MACE), heart failure, and all-cause mortality compared with non-surgical care.

Practitioners can consider metabolic bariatric surgery as an effective option for achieving weight loss and reducing cardiovascular risks.

Stroke is inversely associated with fat intake from supplements and PUFA intake from diet.

Increasing intake of specific fats, particularly PUFA, may help in stroke prevention.

The campaign intervention included features such as a thematic framework and an incentive-based point system targeting behavioral goals.

Incorporating thematic and incentive-based elements may enhance engagement in weight loss interventions.

The incidence of using hypoglycemic drugs was 36.15% in the plate model compared to 75.54% in the low-fat model (P<0.001).

Implementing the plate model may significantly reduce the need for hypoglycemic medications in newly diagnosed type 2 diabetes patients.

Individuals with type 2 diabetes mellitus are at substantial risk of cardiovascular disease.

Healthcare providers should closely monitor cardiovascular health in diabetic patients.

A median SPAN score (52.8) was associated with a 41% lower risk of MACE (HR: 0.59; 95% CI: 0.49, 0.70).

Practitioners should aim for a balanced SPAN score to lower cardiovascular event risk.

Omega-3 fatty acids play a role in lipolysis and can lead to improved body composition.

Incorporating omega-3 fatty acids may help individuals seeking to reduce body fat and improve physical performance.

For the low-fat diet, income, leptin, education, low-density lipoprotein, and dietary adherence at baseline are significant predictors of weight loss success.

Practitioners should assess these factors when advising on low-fat diets.