Browse the evidence

Both constant load and ascending pyramidal load resistance training improve phase angle in older women after eight weeks.

Practitioners can use either training method to enhance phase angle in older female clients.

51% of women randomized to the POWER-remote intervention lost ≥5% of their baseline body weight at 6 months, compared to 12% in the self-directed arm.

Remote weight loss interventions can be effective for breast cancer survivors.

Low-carbohydrate, high-fat diets demonstrate benefits in terms of obesity, diabetes, dyslipidemia, and metabolic derangement.

Practitioners may consider recommending low-carbohydrate, high-fat diets for improving metabolic health.

Monounsaturated and polyunsaturated fatty acids, especially n-3 PUFAs, favor metabolic markers and are key components of the Mediterranean Diet.

Incorporating monounsaturated and polyunsaturated fats into diets may enhance metabolic health.

Obesity surgery is indicated for patients with BMI ≥ 40 kg/m² or BMI ≥ 35 kg/m² with obesity-related comorbidities.

Practitioners should consider obesity surgery for patients meeting these BMI criteria and with relevant comorbidities.

Metabolic surgery for type 2 diabetes is indicated for patients with BMI ≥ 30 kg/m² and as a primary indication for those with BMI ≥ 40 kg/m².

Practitioners should evaluate metabolic surgery for diabetic patients who meet these BMI criteria.

Ultraprocessed foods facilitate overconsumption and may contribute to the development of obesity.

Practitioners should be aware of the potential for ultraprocessed foods to lead to overconsumption and obesity.

Properties of ultraprocessed foods, such as high energy density and low volume, contribute to overconsumption.

Understanding these properties can help practitioners guide consumers towards healthier food choices.

Limiting saturated fatty acids intake to <10% of total caloric intake in obesity and <7% in hypercholesterolemia is recommended.

Practitioners should advise patients to limit saturated fat intake according to these guidelines.

Daily dietary fiber intake should reach a level of 25-40 g.

Encourage patients to increase their dietary fiber intake to meet these levels.

Vegetables and fruits should be consumed at a daily minimum level of 200g (or 4-5 portions) each.

Advise patients to include at least 200g of vegetables and fruits in their daily diet.

High-velocity resistance training (HVRT) increases muscle strength, muscle thickness, and some measures of peak torque and physical performance in untrained healthy aging males.

Practitioners can use HVRT to effectively improve muscle strength and performance in older adults.

Creatine supplementation augments gains in leg press and total lower-body strength compared to placebo.

Incorporating creatine supplementation can enhance strength training outcomes for older adults.

High-velocity resistance training and creatine supplementation are safe interventions for aging adults.

These interventions can be safely recommended for older adults looking to improve fitness.

Using tirzepatide resulted in a weight loss of 17.8% compared with 12.4% for semaglutide.

Tirzepatide may be more effective for weight loss in patients with type 2 diabetes.

Plant-based diets with healthful complex carbohydrates reduced cardiovascular disease (CVD).

Encourage patients to adopt plant-based diets with complex carbohydrates to lower CVD risk.

High-dose omega-3 fatty acids lower triglycerides, reduce CVD, and prevent coronary plaque progression.

Consider recommending high-dose omega-3 supplements for patients at risk of CVD.

Individuals should minimize saturated fats and refined carbohydrates, eliminate trans-fat, and increase fruits, vegetables, whole grains, low-fat dairy, and fish or other omega-3 fatty acids.

Advise patients to follow these dietary guidelines to improve heart health.

Multiple risk factors should be targeted simultaneously in T2DM patients to reduce CV events.

A comprehensive approach addressing multiple risk factors is essential for effective cardiovascular disease prevention in T2DM patients.

Dietary protein recommendations for older adults should be increased to mitigate age-related decline in skeletal muscle.

Practitioners should consider recommending higher protein intake for older adults to support muscle health.

Alternative protein sources may support muscle anabolism in active older adults.

Practitioners should explore alternative protein sources for their potential benefits in older adults.

Tirzepatide treatment significantly reduced the 10-year predicted risk of developing type 2 diabetes compared with placebo in participants with obesity or overweight.

Practitioners can consider tirzepatide as an effective intervention for reducing diabetes risk in overweight or obese patients.

At week 72, mean absolute T2D predicted risk score reductions were significantly greater in tirzepatide groups (5 mg, 12.4%; 10 mg, 14.4%; 15 mg, 14.7%) versus placebo (0.7%).

The specific dose of tirzepatide can be tailored to achieve greater reductions in diabetes risk.

For participants with and without prediabetes, risk reductions were significantly greater in tirzepatide groups versus placebo.

Tirzepatide may be beneficial for a broader range of patients, including those with prediabetes.