Browse the evidence

Resistance training frequency does not significantly affect changes in muscle mass.

Increasing resistance training frequency may not lead to greater muscle mass gains.

Protein supplementation during aerobic training did not significantly enhance cardiorespiratory fitness compared with an isocaloric placebo.

Practitioners should consider that protein supplementation may not provide additional benefits for improving cardiorespiratory fitness in stroke patients undergoing aerobic training.

Resistance training intensity was less than 40% of 1 repetition maximum in both young and older adults.

Practitioners should be aware that low-load resistance training may not effectively increase muscle strength and mass.

The low-intensity resistance training program may be insufficient for increasing muscle strength and mass among both young and older adults.

Low-intensity resistance training may not be adequate for rehabilitation goals related to muscle strength.

Supplementation often fails to improve protein balance or related physiological and performance outcomes under severe operational stress.

Practitioners should consider that protein supplementation may not be beneficial in high-stress operational environments.

There was no significant relationship between body fat mass changes and daily protein intake.

Practitioners should note that increasing protein intake may not affect body fat loss in older women.

The FINDRISC questionnaire is predictive of impaired glucose metabolism in 55% of cases but less efficient in identifying individuals with IGT at 16%.

Healthcare practitioners can use the FINDRISC questionnaire to screen for impaired glucose metabolism effectively.

Mortality rates from CVD and all-cause mortality declined significantly among men with diabetes from 1971 to 2000, but not among women with diabetes.

This indicates a need for targeted interventions for women with diabetes to address mortality disparities.

Weight loss from dieting has not shown similar mortality benefits as bariatric surgery.

Weight loss strategies should consider the limitations of dieting compared to surgical options.

Cardiovascular events did not decrease in obese and overweight diabetics despite a median weight loss of 6%.

Weight loss alone may not be sufficient to improve cardiovascular health in this population.

Bariatric surgery reduces the risk for overall cancer incidence, particularly female cancers.

Bariatric surgery may lower cancer risk, especially in women.

Bariatric surgery increases the risk for alcohol use disorders, particularly in gastric bypass operated patients.

Patients should be monitored for alcohol use disorders after bariatric surgery.

In overweight and obese subjects undergoing a Mediterranean-type low-calorie diet, a different distribution of daily protein intake between meals and snacks does not result in significant differences in terms of fat mass loss and lean mass maintenance.

Practitioners can consider that protein distribution throughout the day may not significantly impact fat loss or muscle maintenance in similar dietary contexts.

In insulin resistance, endothelin-1 is directly involved in regulating muscle glucose uptake.

Understanding the role of ET-1 may help in developing targeted therapies for insulin resistance.

ALOXE3 is activated during fasting and enhances insulin sensitivity via hepatic PPARγ.

Targeting ALOXE3 may be a viable strategy for improving insulin sensitivity in metabolic diseases.

Hepatocyte-specific ALOXE3 expression reduces weight gain and hepatic steatosis.

Enhancing ALOXE3 expression could be a strategy for reducing obesity-related liver issues.

Thiazolidinediones (TZDs) are associated with weight gain, limiting their use as first-line agents for type 2 diabetes.

Practitioners should be cautious in prescribing TZDs due to their association with weight gain.

The mortality of German type 2 diabetes (T2D) patients is approximately 3.1 times higher than that of the general population.

Healthcare providers should be aware of the significantly higher mortality risk in T2D patients compared to the general population.

The cardiovascular risk in the current DMP for T2D patients is not adequately addressed, indicating potential for improvement.

There is a need for healthcare systems to enhance cardiovascular care in T2D management programs.

Patients undergoing gastric bypass surgery have a higher risk of postoperative alcohol use disorders compared to those undergoing restrictive procedures.

Clinicians should monitor gastric bypass patients for signs of alcohol use disorders.

Physical activity was associated with decreased fasting glucose, but this was not significant after adjusting for age and BMI.

While physical activity may lower fasting glucose, practitioners should consider age and BMI as significant factors.

Twenty percent of survey respondents had a high overall score on the Eating Attitudes Test (EAT-26), indicating high rates of disordered eating behaviors.

Practitioners should be aware of the prevalence of disordered eating in this population when addressing weight loss.

All interview participants reported engaging in and/or observing disordered eating behaviors in efforts to lose weight.

Understanding the social dynamics of disordered eating can inform interventions.

Disordered eating behaviors produced ripples of embodied experiences affecting family, friends, and coworkers of dieters.

Practitioners should consider the social context of disordered eating when developing support strategies.