27,684 findings
- Energy balanceStrong
Concerns exist regarding the cardiovascular safety of diets, particularly related to weight fluctuations and ketogenic diets.
Practitioners should be cautious about the cardiovascular implications of certain diets.
Qualifies 2024 - Energy balanceStrong
There is currently no definitive evidence that carbohydrate reduction per se durably lowers glycaemia in type 2 diabetes.
Caution against assuming that reducing carbohydrates will always improve glycaemic control.
Refutes 2024 - HormonalStrong
Medication adherence increased from 52.8% to 84%.
Encouraging medication adherence can significantly improve patient outcomes.
Supports 2025New - Energy balanceStrong
Pre-intervention, the score of the survey of adherence to the Mediterranean diet was relatively low (7.44 ± 0.22 points).
Understanding baseline adherence levels can help tailor interventions effectively.
Supports 2025New - HormonalStrong
In women, an ILI-associated decrease in estradiol of 14% from baseline to year 1 mediated a decline in whole-body BMD of -1.15 mg/cm2.
Practitioners should consider the hormonal changes in postmenopausal women when implementing weight loss interventions.
Supports 2025New - HormonalStrong
In men, an ILI-associated increase of 11% in total testosterone mediated a decline of hip BMD of -1.18 mg/cm2.
Practitioners should consider the hormonal changes in older men when implementing weight loss interventions.
Supports 2025New - HormonalStrong
ILI-associated changes in estradiol and total testosterone resulted in whole-body and hip bone loss.
Weight loss interventions may lead to hormonal changes that affect bone health in older adults.
Supports 2025New - CellularStrong
The concept of diabesity is based on the twin epidemics of obesity and diabetes.
Healthcare providers should understand the link between obesity and diabetes in managing diabesity.
Supports 2025New - CellularStrong
Lipotoxicity and inflammation cause insulin resistance in the liver and muscle.
Understanding these mechanisms can aid in developing treatment strategies for insulin resistance.
Supports 2025New - Energy balanceStrong
The majority of patients with type 2 diabetes (T2D) had not reached the treatment goals for HbA1c, LDL-C, or blood pressure.
Healthcare providers should focus on improving risk factor control in T2D patients.
Supports 2014 - Energy balanceStrong
An increase in carbohydrate intake at the expense of fat intake is believed by some authors to be responsible for the obesity epidemic in North America and parts of Europe.
Practitioners should consider the implications of carbohydrate and fat intake on obesity.
Supports 2018 - Energy balanceStrong
Obesity rates are rising in China despite a shift from a traditional low-fat, high-carb diet to a relatively high-fat, lower-carb diet.
Practitioners should be cautious about attributing obesity solely to dietary macronutrient composition.
Refutes 2018 - Energy balanceStrong
The T2D prediction model achieves 95.27% ROC-AUC, with 88.48% sensitivity and 87.19% specificity.
The model can be effectively used for early detection of T2D in diverse populations.
Supports 2026New - Energy balanceStrong
The model handles missing data naturally without complex preprocessing and imputation.
The model's ability to manage incomplete data makes it suitable for real-world applications.
Supports 2026New - Metabolic adaptationStrong
Insulin resistance in aging is a multisystem phenomenon reflecting declining metabolic adaptability rather than a simple glucose disorder.
Practitioners should consider insulin resistance as a complex, systemic issue in older patients, not just a glucose management problem.
Supports 2026New - CellularStrong
Age-related insulin resistance arises from interconnected mechanisms, including inflammaging, cellular senescence, and mitochondrial dysfunction.
Understanding these interconnected mechanisms can help in developing targeted interventions for older adults.
Supports 2026New - CellularStrong
Muscle metabolic quality, rather than adiposity alone, emerges as a key determinant of insulin sensitivity in older adults.
Emphasizing muscle quality in interventions may improve insulin sensitivity in older patients.
Supports 2026New - CellularStrong
Innovative obesity therapies could transform long-term outcomes of preeclampsia.
Practitioners should stay informed about new obesity therapies that may improve long-term health outcomes for women with preeclampsia.
Supports 2026New - CellularStrong
Modern research has identified various factors that modulate insulin resistance, indicating the need for targeted therapies.
Identifying modulating factors can help in developing personalized treatment strategies for insulin resistance.
Supports 2026New - Energy balanceStrong
The type of diet that may be most beneficial for weight loss remains controversial.
Practitioners should be aware of the ongoing debate regarding diet effectiveness.
Qualifies 2021 - Energy balanceStrong
No significant differences were seen between groups in energy intake (EI), eating rate (ER), or energy expenditure.
Practitioners should be aware that adding the ELMM device did not significantly change energy intake or expenditure outcomes.
Refutes 2018 - Energy balanceStrong
The most beneficial type of diet for weight loss remains up for debate.
Practitioners should be aware of the ongoing discussions about diet effectiveness.
Qualifies 2024 - CellularStrong
The visual-textual integrator of iFood achieved an accuracy of 51.38% in identifying diet images and information.
The accuracy of the app's data integration can be improved for better dietary insights.
Supports 2022 - Energy balanceStrong
Current genomic risk scores alone may not lead to superior weight loss.
Practitioners should not rely solely on genomic risk scores for weight loss strategies.
Refutes 2026New